Synthesis of ring labeled [1'-14C]-L-tyrosine

• Autorzy: Kański R. , Augustyniak W. , Kańska M.
• Konferencja: Proceedings of the IV All-Polish Conference on Radiochemistry and Nuclear Chemistry9-11 May 2005, Kraków-Przegorzały, Poland
• Języki publikacji: EN

Abstrakty

EN

The synthesis of specifically ring labeled isotopomer of L-tyrosine, (l-Tyr), using chemical and enzymatic methods is reported. The carbon-14 labeled [1’-14C]-L-Tyr has been synthesized by a 6-step conversion of [2-14C]-malonic acid into [4’-14C]-phenol and its subsequent condensation with S-methyl-L-cysteine using enzyme tyrosine phenol lyase from Citrobacter freundii.

Słowa kluczowe

EN

carbon-14; labeling; tyrosine; enzyme; optical isotopomer

• Wydawca: Institute of Nuclear Chemistry and Technology
• Czasopismo: Nukleonika
• Rocznik: 2006
• Tom: Vol. 51,suppl.2
• Strony: 13--16
• Opis fizyczny: Bibliogr. 15 poz., rys.

Twórcy

autor

Kański R.

autor

Augustyniak W.

autor

Kańska M.

• Department of Chemistry, University of Warsaw, 1 Pasteura Str., 02-093 Warsaw, Poland, Tel.: [phone] ext. 509, Fax: [phone],

Bibliografia

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