Reactions of Nitroimidazodihydrooxazole with Alcohols and Phenols in the Presence of Potassium Carbonate

• Autorzy: Żwawiak J. , Gzella A. , Zaprutko L.
• Języki publikacji: EN

Abstrakty

EN

Dihydrooxazole ring opening reactions in bicyclic nitroimidazodihydrooxazoles with simultaneous Williamson ethe real groups formation are described. It was found that only mutual action of K2CO3, phenol and alcohol can cause such reaction. Its mechanism consists of three steps. In a result, a series of 3-phenoxy-1-(5-alkoxy-4-ni tro- 1H-imidazol-1-yl)propan-2-ols has been obtained. The structure of new compounds was confirmed by single crystal X-ray analysis.

Słowa kluczowe

EN

nitroimidazoles; nitroimidazodihydrooxazoles; ring opening reaction; Williamson ether synthesis

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2009
• Tom: Vol. 83, nr 7
• Strony: 1309--1315
• Opis fizyczny: Bibliogr. 23 poz., rys.

Twórcy

autor

Żwawiak J.

autor

Gzella A.

autor

Zaprutko L.

• Poznan University of Medical Sciences, Chair and Department of Organic Chemistry, Grunwaldzka 6, Poznań 60-780, Poland Tel.: [phone]; Fax: [phone]

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