Intermediates in the von Pechmann Reaction

• Autorzy: Nowakowska E. M. , Zaleski J. , Kyzio J. B.
• Języki publikacji: EN

Abstrakty

EN

Condensation of meta-cresol with ethyl acetoacetate in dehydrated phosphoric acid is slow enough to observe formation and disappearance of the in termediates viz 1,2- di -hydro-4,7-dimethyl-4-(4-hydroxy-2-methylphenyl)-coumarin (3) and 1,2- di hydro- 4,7-dimethyl-4-(2-hydroxy-4-methylphenyl)-coumarin (4). GCMS analyses of the reaction mixtures indicated that 4,7-dimethylcoumarin (5) was formed from 3 and 4 by elimination of meta-cresol molecule. The compounds 3 and 4 were isolated by the column chromatography. Their structures were elucidated by the spectroscopic methods but unequivocal assignment of the structure to the particular isomer was not possible. The structures were resolved by X-ray diffraction studies.

Słowa kluczowe

EN

von Pechmann reaction; coumarins; X-ray diffraction; molecular structure; hydrogen bond

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2008
• Tom: Vol. 82, nr 7
• Strony: 1399--1399
• Opis fizyczny: –1402, Bibliogr. 11 poz., rys.

Twórcy

autor

Nowakowska E. M.

autor

Zaleski J.

autor

Kyzio J. B.

• Institute of Chemistry, University of Opole, 45-052 Opole, ul. Oleska 48, Poland,

Bibliografia

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