Tytuł artykułu
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Języki publikacji
Abstrakty
In search of a specific galanin receptor antagonist, 15-amino-acid-residue analogues of porcine galanin modified in position 14 were synthesized and their activity was studied on isolated rat smooth muscles. It was shown that all galanin analogues contracted rat gastric fundus strips in a concentration-dependent manner with significantly increased activities as compared to GAL(1-15)NH2. The results suggest that position 14 in the amino acid sequence of GAL(1-15)NH2 is important for the biological activity.
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Czasopismo
Rocznik
Tom
Strony
1375--1384
Opis fizyczny
Bibliogr. 45 poz., rys.
Twórcy
autor
autor
autor
autor
autor
- Faculty of Chemistry, University of Gdańsk, Sobieskiego 18, 80-952 Gdańsk, Poland
Bibliografia
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUJ5-0018-0004