Synthesis and Characterization of Some 1-Halophenyl-4-nitroimidazoles

• Autorzy: Jędrysiak R. , Suwiński J.
• Języki publikacji: EN

Abstrakty

EN

Several 1-(chloro, fluoro, dichloro or difluorophenyl)-4-nitroimidazoles and their 2-methyl derivatives have been prepared by the reaction of respectively substituted anilines with 1,4-dinitroimidazoles via a degenerated imidazole ring transformation. The structures of the obtained products were characterized by spectros copy and/or by X-ray analysis. Most of the products have been tested as My cobacterium tuberculosis inhibitors.

Słowa kluczowe

EN

nitroimidazoles; nucleophilic substitution; AM1 calculations; tuberculosis

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2007
• Tom: Vol. 81, nr 11
• Strony: 1935--1948
• Opis fizyczny: Bibliogr. 21 poz., rys.

Twórcy

autor

Jędrysiak R.

autor

Suwiński J.

• Faculty of Chemistry, Silesian University of Technology, Krzywoustego 4, 44-100 Gliwice, Poland,

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