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Abstrakty
The synthesis of five isotopomers of L-DOPAlabelled selectivelywith deuterium, tritium and 14C is reported. The isotopomers of L-tyrosine, the intermediate substrates for this synthesis, were obtained using chemical and enzymatic methods. Selectively labelled isotopomers of L-tyrosine were hydroxylated respectively to [3R-3H]-L, [5-2H]-L, [2 ,6 -2H2]-L, doubly labelled [5-2H/3H]-L, and [1-14C]-L-DOPA using activity of enzyme tyrosine (EC 1.14.18.1) isolated from mushrooms.
Wydawca
Czasopismo
Rocznik
Tom
Strony
1763--1763
Opis fizyczny
–1769, Bibliogr. 39 poz., rys.
Twórcy
autor
autor
- Department of Chemistry, University of Warsaw, Pasteur 1 Str., 02-093 Warsaw, Poland, mkanska@chem.uw.edu.pl
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUJ5-0017-0009