Synthesis and Rearrangement of 2-(N-Methyl-N-nitroamino)-4-phenylthiazole

• Autorzy: Spaleniak G. , Daszkiewicz Z. , Kyzio J.
• Języki publikacji: EN

Abstrakty

EN

2-(N-Methyl-N-nitroamino)-4-phenylthiazole (5) was prepared and rearranged in aqueous dioxane under influence of sulphuric acid of various concentrations. 2-(N-Methylamino)- 5-nitro-4-phenylthiazole (6) was the only product up to 50% acid concentration. At higher acidities, significant amounts of nitro derivatives 3b and3c, substituted in benzene ring, were also formed. The result indicates that migration of the N-nitro group occurs on the intramolecular path, however, in concentrated sulphuric acid, formation of nitronium ion and ring nitration also takes place.

Słowa kluczowe

EN

Hantzsch synthesis; Angeli method; nitramine rearrangement; mechanism of migration

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2007
• Tom: Vol. 81, nr 2
• Strony: 171--178
• Opis fizyczny: Bibliogr. 16 poz., rys.

Twórcy

autor

Spaleniak G.

autor

Daszkiewicz Z.

autor

Kyzio J.

Bibliografia

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