Identyfikatory
Warianty tytułu
Języki publikacji
Abstrakty
Four transition metals complexes ([Mn(L)2] (complex 1), [Ni(L)20.5H2O] (complex 2), [Cu(L)24H2O] (complex 3) and [Zn(L)20.5H2O] (complex 4)), which contain a new Schiff base ligand (HL) derived from 2,4-dihydroxylacetophenone with triaminotriethylamine, have been synthesized and subsequently characterized by element analysis, 1HNMRand mass spectra. Their properties have been investigated by IR, UV and TG-DTA techniques. Tentative structures for the complexes have been proposed based on the experimental results. The antitumor activity against HL-60 human leukemia cells of free ligand (L) and its Mn(II), Ni(II), Cu(II) complexes were also studied by MTT method. The Ni(II) complex shows the best antitumor activity properties among these complexes.
Wydawca
Czasopismo
Rocznik
Tom
Strony
1657--1662
Opis fizyczny
Bibliogr. 14 poz., rys.
Bibliografia
- 1. Frausto da Silva J.J. and Williams R.J.R, The Biological Chemistry of the Elements, Clarendon Press, Oxford, 1991, p. 302.
- 2. Endeben A. and Schumacher D., Eur. J. Inorg. Chem., 3039 (2001).
- 3. Yu S.Y., Wang S.X., Luo Q.H. and Wang L.F., Polyhedron, 12,1097 (1993).
- 4. Li J., Tang S.M., Zhang F.X., Tang Z.X., Shi Q.Z., Wu QJ. and Huang Z.X., Chinese J. Inorg. Chem., 16, 84 (2000).
- 5. Chen H.L., Hań D.Y., Hań H., Tang W.X., Yang Y. and Yang W.T., Acta Cryst., C52, 2204 (1996).
- 6. Padhy S. and Kauffman G.B., Coord. Chem. Rev., 63,127 (1985).
- 7. Garoufis A., Kasselouri S., Katehanakis A., Kalkanis S., Gerlepes S.P. and Hadjiliadis N., Inorg. Chim. Acta, 207,255 (1993).
- 8. Yang T.L., Xiao Z.F, Qin W.W. and Liu W.S., Polish J. Chem., 78 , 601 (2004).
- 9. Yang T.L., Qin W.W. and Liu W.S., Talanta, 62,451 (2004).
- 10. Patricia R and Trevor J.M., Cancer Res„ 50,1392 (1990).
- ll. Geary W.J., Coord. Chem. Rev.,7, 81 (1971).
- 12. Elicchi Ferrari M.B., Capacchi S., Bisceglie F., Pelosi G. and Tarasconi R, Inorg. Chim. Acta, 32,81(2001).
- 13. Nakamoto K., Infrared and Raman Spectra of Inorganic and Coordination Compounds, NY: Wiley & Sons, 1978.
- 14. Dodoff N., Grancharow K. and Gugova R., J. Inorg. Biochem., 54, 212 (1994).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUJ5-0005-0008