Potentiometric and Thermodynamic Studies of Azosulfonamide Drugs

• Autorzy: Al-Sarawy A. , El-Bindary A. , El-Sonbati A. , Mokpel M.
• Języki publikacji: EN

Abstrakty

EN

The dissociation constants of azosulfonamide derivatives of rhodanine have been determined potentiometrically in 0.1 M-KCl and 10 vol. % DMF-water mixture. The data are discussed in terms of electron nature of the substituents and of the change in temperature. The pK1 H values have been found to increase with increasing electron-donating nature of the substituents. The evaluated thermodynamic parameters (delatG, deltaH, and deltaS) indicated that the dissociation processes are not spontaneous; they are endothermic and entropically unfavourable.

Słowa kluczowe

EN

azosulfonamide; potentiometry and thermodynamic

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2006
• Tom: Vol. 80, nr 2
• Strony: 289--295
• Opis fizyczny: Bibliogr. 16 poz.

Twórcy

autor

Al-Sarawy A.

autor

El-Bindary A.

autor

El-Sonbati A.

autor

Mokpel M.

• Department of Mathematical and Physical Sciences, Faculty of Engineering, Mansoura University, Mansoura, Egypt

Bibliografia

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