Asymmetric Synthesis of Multi-substituted Indolizidines by Intramolecular Addition of Allylsilane to Chiral 2,3-Dihydro-4-pyridones

• Autorzy: Furman B. , Frelek J. , Dziedzic M. , Kamińska A.
• Języki publikacji: EN

Abstrakty

EN

A short and synthetically attractive asymmetric synthesis of substituted indolizidines is described. The discovered reaction sequence consists of the asymmetric aza-Diels-Alder reaction of aldimines with Danishefsky's diene and the intramolecular Hosomi-Sakurai allylation. The absolute configuration of cycloadducts was established by CD-spectroscopy

Słowa kluczowe

EN

asymmetric synthesis; chiral dihydopyridones; conjugate addition; allylsilanes

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2005
• Tom: Vol. 79 / nr 12
• Strony: 1919--1928
• Opis fizyczny: Bibliogr. 23 poz.

Twórcy

autor

Furman B.

• Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 02-224 Warsaw, Poland

autor

Frelek J.

• Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 02-224 Warsaw, Poland

autor

Dziedzic M.

• Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 02-224 Warsaw, Poland

autor

Kamińska A.

• Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 02-224 Warsaw, Poland

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