Synthesis of (1S,2S)- and (1R,2S)-3-Amino-1,2-dihydroxypropylphosphonic Acids

• Autorzy: Wróblewski A. , Głowacka I.
• Języki publikacji: EN

Abstrakty

EN

(1S,2S)- and (1R,2S)-3-amino-1,2-dihydroxypropylphosphonic acids were synthesized from (S)-3-azido-2-benzyloxypropanal in two steps, which involved addition of dibenzyl phosphite, clean separation of dibenzyl (1S,2S)- and (1R,2S)-3-azido-2-benzyloxy-1- hydroxypropylphosphonates followed by azide reduction with simultaneous hydrogenolysis of benzyl protecting groups.

Słowa kluczowe

EN

3-aminophosphonic acids; 1-hydroxyphosphates; configuration; conformation

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2005
• Tom: Vol. 79 / nr 12
• Strony: 1895--1899
• Opis fizyczny: Bibliogr. 16 poz.

Twórcy

autor

Wróblewski A.

• Bioorganic Chemistry Laboratory, Faculty of Pharmacy, Medical University of Łódź, 90-151 Łódź, Muszyńskiego 1, Poland

autor

Głowacka I.

• Bioorganic Chemistry Laboratory, Faculty of Pharmacy, Medical University of Łódź, 90-151 Łódź, Muszyńskiego 1, Poland

Bibliografia

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