Limbatolide F and G: Two New trans-Clerodane Diterpenoids from Otostegia limbata

• Autorzy: Farooq U. , Khan A. , Ahmad V. , Kousar F. , Iqbal S.
• Języki publikacji: EN

Abstrakty

EN

Two new trans-clerodane diterpenoids pro vi sion ally named as limbatolide F (1) and limbatolide G (2) were isolated from the chloroform extract of Otostegia limbata. Both compounds 1 and 2 have a unique feature of C-4/C-6 five membered a,b-un saturated lactone. The structures of these new compounds as well as their relative configurations were determined by 1D and 2D NMR techniques including COSY, HMQC, HMBC, NOESY and NOE experiments.

Słowa kluczowe

EN

Otostegia limbata; trans-clerodane; diterpenoids; Lamiaceae

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2005
• Tom: Vol. 79 / nr 11
• Strony: 1757--1762
• Opis fizyczny: Bibliogr. 12 poz., rys.

Twórcy

autor

Farooq U.

• International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, Uni versity of Karachi, Karachi - 75270, Pakistan

autor

Khan A.

• International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, Uni versity of Karachi, Karachi - 75270, Pakistan

autor

Ahmad V.

• International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, Uni versity of Karachi, Karachi - 75270, Pakistan

autor

Kousar F.

• International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, Uni versity of Karachi, Karachi - 75270, Pakistan

autor

Iqbal S.

• International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, Uni versity of Karachi, Karachi - 75270, Pakistan

Bibliografia

• 1.Citoglu G., Tanker M., Sever B., Englest J., Anton R. and Altanlar N., Planta Med., 64.484 (1998).
• 2.Ali S.I. and Nasir E., Flora of West Pakistan, Fakhri Printing Press, Karachi, Pakistan 1972, p. 627.
• 3.Chopra R.N., Nayar S.I. and Chopra I.C., Glossary of Indian Medicinal Plants, Indian Council of Scientific & Industrial Research, India 1956, p. 183.
• 4.Vural K., Ezer N., Erol K. and Sahin F.P., J. Fac. Pharm. Gazi, 13, 29 (1996).
• 5.Eshbakova K.A., Sagitdinova G.V., Levkovich M.G., Rasulev B.F., Abdullaev N.D. and Malikov V.M., Chem. Nat. Compd., 33, 458 (1997).
• 6.Ahmad V.U., Farooq U., Abbaskhan A., Hussain J., Abbasi M.A., Nawaz S.A. and Choudhary M.I., Helv. Chim. Acta, 87, 682 (2004).
• 7.Ahmad V.U., Farooq U., Hussain J., Farman U., Nawaz S.A. and Choudhary M.I., Chem. Pharm. Bull., 52, 441 (2004).
• 8.Heymann H., Tezuka Y., Kikuchi T. and Supriyatna S., Chem. Pharm. Bull., 42, 1202 (1994).
• 9.Kitagawa I., Simanjuntak P., Hori K., Nagami N., Mahmud T., Shibuya H. and Kobayashi M., Chet Pharm. Bull., 42, 1050(1994).
• 10.Krishna V. and Singh P., Phytochemistr, 52, 1341 (1999).
• 11.Rivera A.P., Faini F. and Castillo M., J. Nat. Prod., 51, 155 (1988).
• 12.Manabe S. and Nishino C., Tetrahedron, 42, 3461 (1986).