Lipase-Catalysed Resolution of 1-Hydroxyethane-P-phenylphosphinates

• Autorzy: Majewska P. , Kafarski P. , Lejczak B.
• Języki publikacji: EN

Abstrakty

EN

Lipase-catalysed hydrolysis and transesterification were used to obtain _-hydroxyalkanephosphinates with two stereogenic centers, namely at_-carbon and phosphorus atoms. These compounds were chosen to check if there is a transfer of chirality from carbon to phosphorus atom during lipase catalysed reactions.

Słowa kluczowe

EN

biocatalysis; kinetic resolution; enantioselectivity; chirality transfer

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2005
• Tom: Vol. 79 / nr 3
• Strony: 561--566
• Opis fizyczny: Bibliogr. poz. 6, rys.

Twórcy

autor

Majewska P.

autor

Kafarski P.

autor

Lejczak B.

• Institute of Organic Chemistry, Biochemistry and Biotechnology, Technical University of Wrocław, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland

Bibliografia

• 1. For review see: Kafarski P. and Lejczak B., J. Mol. Catal. B: Enzym., 29, 99 (2004).
• 2. Shioji K., Tashiro A., Shibata S. and Okuma K., Tetrahedron Lett., 44, 1103 (2003).
• 3. Texier-Boullct F. and Lequitte M., Tetrahedron Lett., 27, 3515 (1986).
• 4. Li Y-F. and Hammerschmidt F., Tetrahedron: Asym., 4, 109 (1993).
• 5. Shioji K., Ueno Y., Kurauchi Y. and Okuma K., Tetrahedron Lett., 42, 6569 (2001).
• 6. Skwarczyński M., Lejczak B. and Kafarski P., Chirality, 11, 109 (1999).