Deuterium Isotope Effects of 0-Hydroxythioamides, Thiazolines and 5-Acyl-2-thiobarbituric Acids

• Autorzy: Hansen P. , Duus F. , Neumann R. , Wesolowska A. , Sosnicki J. , Jagodzinski T.
• Języki publikacji: EN

Abstrakty

EN

Deuterium isotope effects on 13C chemical schifts are studied in a series of o-hydroxythioamides, 2 delta-thiazolines and enolic 5-acyl-2-thiobabituric acids. Novel 2-hydroxy-1-thiocarboxamide naphthalenes show steric isotope effects of opposite sign to those observed in 2-hydroxy-1-acetylnaphthalenes and pyrenes. The o-hydroxyaromatic 2delta-thiazolines show tautometric behaviour and accordingly large isotope effects. Tautomerism of these and the thioamides are discussed in relation to structure. Intramolecular hydrogen bonding of non-RAHB type show only weak effects. The enolic mono N-alkyl 5-acyl 2-thiobarbituric acids show two isomers, both of which are involved in enol-enol tautomerism.

Słowa kluczowe

EN

deuterium isotope effects; chemical shifts; secondary isotope effects; o-hydroxythioamides; thiazolines

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2000
• Tom: Vol. 74, nr 3
• Strony: 409--420

Twórcy

autor

Hansen P.

autor

Duus F.

autor

Neumann R.

autor

Wesolowska A.

autor

Sosnicki J.

autor

Jagodzinski T.

• Department of Life Sciences and Chemistry Roskilde University P.O.Box 260 DK-4000 Roskilde, Denmark