Synthesis of 4-cyanophenyl and 4-nitrophenyl 2,6-anhydro-1,2-dithio-D-manno- and altropyranosides and their derivatives possessing antithrombotic activity

• Autorzy: Bozo E. , Boros S. , Kuszmann J.
• Języki publikacji: EN

Abstrakty

EN

1,3,4-Tri-O-acetyl-2,6-anhydro-2-thio-D-manno- and -D-altropyranose as well as 1,4-di-O-acetyl-2,6-anhydro-3-azido-3-deoxy-2-thio-D-mannopyranose were synthesized and used as donors in the synthesis of the corresponding 4-cyano- and 4-nitrophenyl-thioglycosides, which showed significant oral antithrombotic activity in rats.

Słowa kluczowe

EN

overbridged 2,6-thioanhydro-thioglycosides; antithrombotics

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 1999
• Tom: vol. 73 nr 6
• Strony: 989--1001

Twórcy

autor

Bozo E.

autor

Boros S.

autor

Kuszmann J.