Tytuł artykułu
Identyfikatory
Warianty tytułu
Języki publikacji
Abstrakty
The molecular structure of 8 and 9 has been determined by a single-crystal X-ray analysis. Both chiral esters are derivatives of the non-steroidal anti-inflammatory drug diclofenac (1), and have physicochemical properties of potential prodrug. Comparison of the geometry of 2-[(2,6-dichlorophenyl)amino]phenylacetate fragment, observed in eighteen solid-state structures, shows limited flexibility of 1. Two rotations around bonds linking the o-phenyl ring with the carboxyl and dichlorophenyl groups change their relative orientation, but both groups are nearly perpendicular to the o-phenyl plane. The amino group is involved exclusively in intramolecular contacts.
Słowa kluczowe
Wydawca
Czasopismo
Rocznik
Tom
Strony
367--376
Opis fizyczny
Twórcy
autor
autor
autor
autor
autor
- Wydział Chemii UMCS 20-031 Lublin
Bibliografia
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUJ2-0002-0010