Total Synthesis of the Nephritogenoside Glycopeptide

• Autorzy: Zhang H. , Wang Y. , Thurmer R. , Al-Qawasmeh R. , Voelter W.
• Języki publikacji: EN

Abstrakty

EN

A mild three-dimensional orthogonal protection scheme, based on Nps/Fmoc-groups for a-amino, benzyl residues for hydroxyl and carboxyl protection and 2-chlorotrityl esters as anchoring linkage proved to be a new effective approach for the synthesis of glycopeptides. The oligosaccharide moiety of the nephritogenoside glycopeptide is conveniently assembled via phenyl thioglycosides as glycosyl acceptors and phenyl thioglycosyl sulfoxides as donors, readily accessible from the thioglycosides by oxidation with m-chloroperbenzoic acid.

Słowa kluczowe

EN

glycopeptides; carbohydrates; nephritogenoside

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 1999
• Tom: vol. 73 nr 1
• Strony: 101--115

Twórcy

autor

Zhang H.

autor

Wang Y.

autor

Thurmer R.

autor

Al-Qawasmeh R.

autor

Voelter W.