Lysine-Vasopressin Analogues with Glycoconjugates in Position 8

• Autorzy: Marcinkowska A. , Borovickova L. , Slaninova J. , Grzonka Z.
• Języki publikacji: EN

Abstrakty

EN

Two analogues of lysine-vasopressin in which the lysine side chain was modified by the attachment of glucuronic acid through the amide bond were synthesized and their pharmacological properties evaluated. In comparison to arginine-vasopressin used as a standard, both analogues were found to exhibit low activity in vasopressor test, moderate activity in antidiuretic test, and comparable activity in uterotonic test.

Słowa kluczowe

EN

glycoconjugates; glycopeptides; lysine-vasopressin analogues

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2006
• Tom: Vol. 80, nr 5
• Strony: 759--766
• Opis fizyczny: Bibliogr. 24 poz., rys.

Twórcy

autor

Marcinkowska A.

autor

Borovickova L.

autor

Slaninova J.

autor

Grzonka Z.

• Faculty of Chemistry, University of Gdansk, Sobieskiego 18, 80-952 Gdansk, Poland

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