Studies on 2,3-Dioxopyrrolidines. Synthesis of Piperazine, Pyrrolo[4,5-b]indole, Pyrazino [5,6-b]indole and Arylazo Derivatives of Amino Acids

• Autorzy: Sofan M. , Fouda A. , Asfah E.
• Języki publikacji: EN

Abstrakty

EN

2,3-Dioxopyrrolidines 1 convert into 2,4-diketopiperazines 2 in one pot-reaction with hydrazoic acid. The pyrrolo[4,5-b]indole 6 was obtained by cyclization of p-methoxyphenylhydrazone 4 prepared via Japp-Klingemann reaction of 1a with p-methoxyphenyldiazonium chloride. Compound 5 undergoes Schmidt reaction to give the pyrazino[5,6-b]indole derivative 6. Reaction of 1b with some aryldiazonium chlorides yields arylhydrazono-_-alanines 8 and 9. Phenylhydrazonoglycine derivative 11 was synthesized via Schmidt reaction to 10 with hydrazoic acid.

Słowa kluczowe

EN

piperazine; pyrroloindoles; pyrazinoindoles; Schmidt reaction; Japp-Klingeman reaction

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2004
• Tom: Vol. 78 / nr 6
• Strony: 837--842

Twórcy

autor

Sofan M.

• Faculty of Science, Department of Chemistry, Mansoura University, New Damietta, P.O. Box 34517, Egypt

autor

Fouda A.

• Faculty of Science, Department of Chemistry, Mansoura University, New Damietta, P.O. Box 34517, Egypt

autor

Asfah E.

• Faculty of Science, Department of Chemistry, Mansoura University, New Damietta, P.O. Box 34517, Egypt

• Faculty of Science, Department of Chemistry, Mansoura University, New Damietta, P.O. Box 34517, Egypt

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