Synthesis, Characterization, Spectroscopic and Antimicrobial Activity studies of Pyrimidine Dithiocarbamate Macrocyclic Complexes

• Autorzy: Nishat N. , Rahis-ud-din , Haq M.
• Języki publikacji: EN

Abstrakty

EN

The ligands disodium salts of thiobarbituric acid (Na2L1) and 5,5-diethylbarbituric acid (Na2L2) and their transition metal complexes of the type [M2(L1)2] and [M2(L2)2], where M= Mn(II), Co(II), Ni(II), Cu(II), Zn(II), have been synthesized. The transition metal(II) complexes have been characterized by a range of techniques including IR, 1H NMR,UV-visible spectroscopy, magnetic moment measurements, elemental analyses and molar conductance measurements. The spectroscopic studies indicate, that the reaction of L1and L2 with a divalent metal ions form binuclear dithiocarbamate macrocyclic complexes. The molar conductivity measurements suggest, that all of the complexes are non-electrolytes. The magnetic moment values and electronic spectra reveal that the Ni(II) and Cu(II) complexes are square-planar, while Mn(II), Co(II) and Zn(II) complexes are tetrahedral. All of the compounds have been screened for antimicrobial activity against Staphylococcus aureus (gram-positive bacteria) and Escherichia coli (gram-negative bacteria). The results show that all the compounds inhibit the growth of bacteria. All the complexes showed better activity as compared with the ligands.

Słowa kluczowe

EN

dithiocarbamate ligands; transition metal(II) complexes; antimicrobial activity

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2004
• Tom: Vol. 78 / nr 5
• Strony: 645--652
• Opis fizyczny: Bibliogr. 17 poz., rys.

Twórcy

autor

Nishat N.

• Department of Chemistry, Jamia Millia Islamia (Central University), New Delhi-110025, India

autor

Rahis-ud-din

• Department of Chemistry, Jamia Millia Islamia (Central University), New Delhi-110025, India

autor

Haq M.

• Department of Chemistry, Jamia Millia Islamia (Central University), New Delhi-110025, India

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