Complexes of Cadmium (II) and Mercury(II) with Cytidine 5'-Monophosphate and Diamines in Ternary Systems

• Autorzy: Łomozik L. , Bregier-Jarzębowska R.
• Języki publikacji: EN

Abstrakty

EN

Formation of Cd(II) and Hg(II) complexes in ternary systems with cytidine 5_-monophosphate (CMP) and diamines (en, tn, Put) has been studied. In Hg(II)/CMP/diamine systems the formation of heteroligand compounds is accompanied by the occurrence of non-covalent interactions and the formation of molecular complexes. The presence of polyamine in ternary systems does not change the metal-nucleotide mode of coordination. Similarly as in the binary Hg(II)/CMP system, the metallation involves the donor endocyclic nitrogen N(3) atom and CMP phosphate group. On the other hand, in the Cd(II)/CMP system, the introduction of a polyamine changes the coordination mode of the nucleotide. Phosphate group, inactive in binary systems, takes part in the complexation in ternary systems. In systems of cadmium(II) ions, CMP and diamines, only molecular complexes are formed, in which the polyamine is in the outer coordination sphere. In contrast to Cd(CMP)(H2tn) and Cd(CMP)(H2Put) compounds, in Cd(CMP)(H2en) species the phosphate group of nucleotide does not take part in the metallation, i.e. the metal ion coordinates with CMP, through the atom N(3) of the nucleotide, and the phosphate group is involved in non-covalent interactions with en.

Słowa kluczowe

EN

cadmium(II); mercury(II); cytidine 5'-monophosphate; diamine; complexes

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2004
• Tom: Vol. 78 / nr 4
• Strony: 529--538
• Opis fizyczny: Bibliogr. 43 poz., rys.

Twórcy

autor

Łomozik L.

• Faculty of Chemistry, A. Mickiewicz University, 60-780 Poznań, Grunwaldzka 6, Poland

autor

Bregier-Jarzębowska R.

• Faculty of Chemistry, A. Mickiewicz University, 60-780 Poznań, Grunwaldzka 6, Poland

Bibliografia

• 1. Ebashi S., J. Biochem., 50, 236 (1961).
• 2. Hasselbach W. and Makinose M., Biochemistry, 2, 333 (1961).
• 3. Cohen M., Biochemistry, 2, 623 (1963).
• 4. Sanchez-Cortes S., Molina M., Garcia-Ramos J.V. and Carmona P. J. of Raman Spectroscopy, 22, 819 (1991).
• 5. Zappia V., Progress in Polyamine Research, Ed. Pegg A.E., Plenum Press, NY 1988.
• 6. Diebler H., Secco R and Venturi M., Bioph. Chem., 26, 193 (1987).
• 7. Kopf-Maier P. and Kopf H„ Chem. Rev., 87, 1137 (1987).
• 8. Sherman S.E. and Lippard S.J., Chem. Rev., 87, 1153 (1987).
• 9. Lomozik L„ Wiad. Chem., 48, 439 (1994).
• 10. De Munno G., Mauro S., Pizzino T. and Viterbo D., J. Chem. Soc. Dalton Trans., 1113 (1993).
• 11. Katono Y., Inoue Y. and ChGjo R., Polym. J., 9(5), 471 (1977).
• 12. Srivastawa H.P. and. Tiwari D., J. Indian. Chem. Soc., 70, 499 (1993).
• 13. Walker M.D. and Williams D.R., J. Chem. Soc. Dalton Trans., 1186(1974).
• 14. Martin R.B., Metal ions binding to nucleoside and nucleotides, Ed. A.V. Xavier, Frontiers in Bio-inorganic Chemistry, VCH, Weinheim, 1986.
• 15. Marzilli L.G., Metal complex of nucleic acid derivatives and nucleotides; Binding sites and structures. Eds. Eichhom G.L., Marzilli L.G., Metal Ions in Genetic Information Transfer, EIsevier/North-Holland, Amsterdam, 1981.
• 16. Sigel H., Eur. J. Biochem., 65, 165 (1987).
• 17. Tabor H. and Tabor C.W., Farmacol. Rev., 16, 245 (1964).
• 18. Raina A., Acta Physiol. Scand., 60, 1 (1963).
• 19. Theoharides T.C., Life Sciences, 27, 703 (1980).
• 20. Tabor C.W. and Tabor H., Ann. Rev. Biochem., 45, 285 (1976).
• 21. Seiler N.,J. Chromatog., 379, 157(1986).
• 22. Schuber F., Biochem. J., 260, 1 (1989).
• 23. Tabor C.W. and Tabor H., Annu. Rev. Biochem., 53, 749 (1984).
• 24. Vertino P.M., Bergeron H.J., Cavanaugh P.F. Jr and Porter C.W., Biopolymers, 26, 691 (1987).
• 25. Feuerstein B.G., Pattabiraman N. and Marton L.J., Nucleic Acids Res., 18, 1271 (1990).
• 26. Plum G.E., Arscott P.G. and Bloomfield V.A., Biopolymers, 30, 631 (1990).
• 27. Williams H.G. and Canellakis Z.N., Perspec. Biol. Med., 22, 421 (1973).
• 28. Inne J., P8s6 H. and Raina A., Bioch. Bioph. Acta, 473, 241 (1978).
• 29. Russell D.H., Lewy C.C., Schimpff S.C. and Hawk I.A., Cancer Res., 32, 1555 (1971).
• 30. Horn Y., Stuart L.B., WalachN.,Lubich W.P., SpigelL. and Marton L.J., Cancer Res., 42,3248 (1982).
• 31. Gasowska A. and Lomozik L., Polish J. Chem., 73,465 (1999).
• 32. Lomozik L., Jastrzab R. and Gasowska A., Polyhedron, 19, 1145 (2000).
• 33. Gasowska A., Lomozik L. and Jastrzab R., J. Inorg. Biochem., 78, 139 (2000).
• 34. Irving H.M., Miles M.G. and Pettit L.D., Anal. Chim. Acta, 38, 475 (1967).
• 35. Gans P., Sabatini A. and Vacca A., J. Chem. Soc. Dalton Trans., 1195 (1985).
• 36. Ingri N., Kakolowicz W., Sillen L.G. and Wargvist B., Talanta, 14, 1261 (1967).
• 37. Lomozik L., Jaskolski M. and Wojciechowska A., Polish J. Chem., 65, 1797 (1991).
• 38. Glasoe P.K. and Long F.A., J. Phys. Chem., 64, 188 (1960).
• 39. Lomozik L. and Bregier-Jarzebowska R., Polish J. Chem., 73, 927 (1999).
• 40. Schwarzenbach G. and Szilard I., Helv. Chim. Acta, 45, 1222 (1962).
• 41. Lomozik L., Bregier-Jarzebowska R. and Gasowska A., J. Coord. Chem., 56,203 (2003).
• 42. Lomozik L. and Gasowska A., J. Inorg. Biochem., 72, 37 (1998).
• 43. Lomozik L. and Jastrzab R., J. Inorg. Biochem., 93, 132 (2003).