Effect of Base and Acyl Chloride on Regioselectivity of Acylation of 8,8-Pentamethylene-2-methyl-7,9-dioxa-1-azaspiro[4.5]dec-1-ene 1-Oxide

• Autorzy: Koszytkowska-Stawińska M. , Gębarowski P. , Sas W.
• Języki publikacji: EN

Abstrakty

EN

Acylation of 2-methyl-7,9-dioxa-1-azaspiro[4.5]dec-1-ene 1-oxide (5) in the presence of pyridine gives 3-acyloxy-2-methyl-1-pyrroline derivatives 6 independently of kind of acid chloride, while treatment of 5 with benzoyl or p-nitrobenzoyl chloride and triethylamine affords mainly 2-benzoyloxymethyl- 8a and 2-p-nitrobenzoyloxymethyl-1-pyrroline 8b, respectively. Acetylation of 5 was base-independent.

Słowa kluczowe

EN

2-methyl-1-pyrroline 1-oxide; acylation; regioselectivity

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2004
• Tom: Vol. 78 / nr 2
• Strony: 217--222
• Opis fizyczny: Bibliogr. 15 poz., rys.

Twórcy

autor

Koszytkowska-Stawińska M.

• Warsaw University of Technology, Faculty of Chemistry, ul. Noakowskiego 3, 00-664 Warszawa, Poland Tel: [phone], Fax: [phone]

autor

Gębarowski P.

• Warsaw University of Technology, Faculty of Chemistry, ul. Noakowskiego 3, 00-664 Warszawa, Poland Tel: [phone], Fax: [phone]

autor

Sas W.

• Warsaw University of Technology, Faculty of Chemistry, ul. Noakowskiego 3, 00-664 Warszawa, Poland Tel: [phone], Fax: [phone]

Bibliografia

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