Synthesis of 1,3-Dideoxynojirimycin via an alfa-Amino Aldehyde as a Key Intermediate

• Autorzy: Gryko D. , Jurczak J.
• Języki publikacji: EN

Abstrakty

EN

1,3-Dideoxynojirimycin was synthesized starting from a suitably protected _-amino aldehyde. The crucial step involves addition of allyl bromide to N-benzyl-N-carbobenzoxy- O-tert-butyldimethylsilyl-D-serinal in the presence of tin(II) chloride and sodium iodide.

Słowa kluczowe

EN

1,3-dideoxynojirimycin; alfa-amino aldehydes; Barbier-type addition; allyl addition

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2002
• Tom: Vol. 76 / nr 7
• Strony: 959--965
• Opis fizyczny: Bibliogr. 31 poz., rys.

Twórcy

autor

Gryko D.

• Institute of Organic Chemistry, Polish Academy of Science, Kasprzaka 44/52, 01-224 Warsaw, Poland

autor

Jurczak J.

• Department of Chemistry, Warsaw University, Pasteura 1, 02-093 Warsaw, Poland

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