Tetracyclic Triterpenes. XVII. The Inverted Conformation of Ring A and B in Stereoids: 3-Substituted-4-oxo-14alfa-methyl-5beta-cholest-8-enes

• Autorzy: Joachimiak R. , Martynow J. , Paryzek Z.
• Języki publikacji: EN

Abstrakty

EN

Full assignment of 13C NMR shifts for a series of _8-5_- and 5_-steroids is presented. These data along with some characteristic features of 1H NMR and IR spectra are in accordance with inverted conformation of Aand B rings in 4-oxo-5_-steroids 5 and 6 in solution. Configuration at C-3 is important for inversion of Aand B ring conformation of _-methyl ketones 6 and 7, while the intramolecular hydrogen bonding appears to be responsible for the inverted, slightly distorted chair conformation of ring A in _-hydroxy ketone 5.

Słowa kluczowe

EN

5beta-steroids; inverted conformation; 13C NMR spectra

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2003
• Tom: Vol. 77 / nr 11
• Strony: 1599--1606
• Opis fizyczny: Bibliogr. 28 poz., rys.

Twórcy

autor

Joachimiak R.

• Faculty of Chemistry, Adam Mickiewicz University, Grunwaldzka 6, 60-780 Poznań, Poland

autor

Martynow J.

• Faculty of Chemistry, Adam Mickiewicz University, Grunwaldzka 6, 60-780 Poznań, Poland

autor

Paryzek Z.

• Faculty of Chemistry, Adam Mickiewicz University, Grunwaldzka 6, 60-780 Poznań, Poland

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