Aromatic Nucleophilic Substitution in 1,2,4-triazine 4-Oxides with Grignard Reagents

• Autorzy: Prokhorov A. , Kozhevnikov D. N. , Rusinov V. L. , Chupakhin O. N.
• Języki publikacji: EN

Abstrakty

EN

Addition of the Grignard reagents to 1,2,4-triazine 4-oxides followed by aromatization of the intermediate_H-adducts by dehydrogenation or dehydration was used for synthesis of 5-alkyl- or 5-aryl-substituted 1,2,4-triazines and their 4-oxides.

Słowa kluczowe

EN

1,2,4-triazines; Grignard reagents; sigma-adducts; aromatization; heterocycles

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2003
• Tom: Vol. 77 / nr 9
• Strony: 1157--1161
• Opis fizyczny: Bibliogr. 11 poz., rys.

Twórcy

autor

Prokhorov A.

• Urals State Technical University, 620002, Ekaterinburg, Russian Federation Fax: [phone]

autor

Kozhevnikov D. N.

• Urals State Technical University, 620002, Ekaterinburg, Russian Federation Fax: [phone]

autor

Rusinov V. L.

• Urals State Technical University, 620002, Ekaterinburg, Russian Federation Fax: [phone]

autor

Chupakhin O. N.

• Urals State Technical University, 620002, Ekaterinburg, Russian Federation Fax: [phone]

Bibliografia

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• 2. Iveson P.B., Rivière C., Guillaneux D., Nierlich M., Thuéry R, Ephritikhine M., and Madie C., J. Chem. Soc. Chem. Commun., 1512 (2001).
• 3. Kozhevnikov V.N., Kozhevnikov D.N., Nikitina T.V., Rusinov V.L., Chupakhin O.N., Zabel M. and Koenig B., J. Org. Chem., 68, 2882 (2003).
• 4. Kolarik Z., Mullich U. and Gassner F., Solv. Extr. Ion Exch., 17, 23 (1999).
• 5. Kolarik Z., Mullich U. and Gassner F., Solv. Extr. Ion Exch., 17, 1155 (1999).
• 6. Kozhevnikov D.N., Kozhevnikov V.N., Rusinov V.L. and Chupakhin O.N., Mendeleev Comm., 238 (1997).
• 7. Kozhevnikov D.N., Rusinov V.L. and Chupakhin O.N., Adv. Heterocycl. Chem., Ed. A.R. Katritzky, 82, 261 (2002).
• 8. WebbT.R., Tetrahedron Lett., 26, 3191 (1985).
• 9. (a)Fakhfakh M.A., Franck X., Foumet A., HocquemillerR. and FigadereB., Tetrahedron Lett., 42,3847 (2001); (b) Mani N.S., Chen P. and Jones T.K., J. Org. Chem., 64, 6911 (1999).
• 10. Kozhevnikov D.N., Kozhevnikov V.N., Rusinov V.L., Chupakhin O.N., Sidorov E.O. and Klyuev N.A., Russ. J. Org. Chem., 34, 633 (1998).
• 11. Rykowski A., Chupakhin O.N., Kozhevnikov D.N., Kozhevnikov V.N., Rusinov V.L. and van der Plas U.C., Heterocycles, 55, 127 (2001).