Three New Diterpenoids from Euphorbia decipiens

• Autorzy: Ahmad V. , Hussain H , Jassbi A. R. , Zahid M. , Hussain J. , Bukhari I. A. , Yasin A. , Choudhary M. I
• Języki publikacji: EN

Abstrakty

EN

Three new diterpene esters with a tricyclic myrsinol-type skeleton have been isolated from Euphorbia decipiens Boiss.&Buhse. The structure elucidation of the isolated compounds was based primarily on 1D and 2D-NMR analysis, including COSY, HMQC, HMBC and NOESY correlations. The compound 1 showed inhibitory activity against prolyl endopeptidase and compound 2 showed analgesic activity.

Słowa kluczowe

EN

Euphorbiaceae; diterpene esters; tricyclic diterpenes; myrsinol-type diterpenes; prolyl endopeptidase; Euphorbia decipens Boiss. & Buhse

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2002
• Tom: Vol. 76 / nr 12
• Strony: 1699--1706
• Opis fizyczny: Bibliogr. 16 poz., rys.

Twórcy

autor

Ahmad V.

• H.E.J. Research Institute of Chemistry, International Center of Sciences, University of Karachi, Karachi-75270, Pakistan

autor

Hussain H

• H.E.J. Research Institute of Chemistry, International Center of Sciences, University of Karachi, Karachi-75270, Pakistan

autor

Jassbi A. R.

• H.E.J. Research Institute of Chemistry, International Center of Sciences, University of Karachi, Karachi-75270, Pakistan

autor

Zahid M.

• H.E.J. Research Institute of Chemistry, International Center of Sciences, University of Karachi, Karachi-75270, Pakistan

autor

Hussain J.

• H.E.J. Research Institute of Chemistry, International Center of Sciences, University of Karachi, Karachi-75270, Pakistan

autor

Bukhari I. A.

• H.E.J. Research Institute of Chemistry, International Center of Sciences, University of Karachi, Karachi-75270, Pakistan

autor

Yasin A.

• H.E.J. Research Institute of Chemistry, International Center of Sciences, University of Karachi, Karachi-75270, Pakistan

autor

Choudhary M. I

• H.E.J. Research Institute of Chemistry, International Center of Sciences, University of Karachi, Karachi-75270, Pakistan

Bibliografia

• 1. Rechinger K.H. and Schiman-Czeika H., Flora of Iranica, 1964, vol. 6, p. 33.
• 2. Wu T.S., Lin Y.M., Haruna M., Pan D.J., Shingu T,, Chen Y.P., Hsu H.Y., Nakano T. and Lee K.H, J. Nat. Prod., 54, 823 (1991).
• 3. Shi Y.P., JiaZ.J., Jamil L. and Sadiq S„ Phytochem., 40,1219 (1995).
• 4. Seip E.H. and Hecker E., Phytochem., 22, 1791 (1983).
• 5. Mbwambo Z. H.,Lee S. K., Mshiu E. N.,P ezzuto J.M. and Kinghom A.D.,.J. Nat Prod., 59,1051 (1996).
• 6. Öksüs S., Gürek F., Gil R.R., Pengsuparp T., Pezzuto J.M. and Cordell G.A., Phytochem 38 1457 (1995).
• 7. Anis L, Ahmed S.,Malik A., YasinA. and Choudhary M.I., Chem. Pharm. Bull., 50(4), 515 (2002).
• 8. Ahmad V.U. and Jassibi A.R., Planta Medica, 64, 732 (1998).
• 9. Ahmad V.U. and Jassibi A.R., Phytochem., 47, 1217 (1998).
• 10. Ahmad. V.U, Jassibi A.R. and Parvez M., Tetrahedron, 54, 1573 (1998).
• 11. Zahid M., Hussaini S.R., Abbas M., Pan Y., Jassbi A.R, Asim M., Pervez M., Voelter W. and Ahmad V.U., Hehet. Chim. Acta, 84, 1980 (2001).
• 12. Abbas M„ Jassbi A.R., Zahid M., Ali Z., Alam N., Akhtar F., Choudhary M.I. and Ahmad V. U., Helvet. Chim. Acta., 83, 2751 (2000).
• 13. Lee K-H., Kwak J.H., Lee K-B. and Song K-S., Arch. Pharm. Res., 21, 207 (1998).
• 14. Fan W., Komatsu K., Tezuka Y., Namba T. and Kadota Sh., Biol. Pharm. Bull., 22, 157 (1999).
• 15. Kim J-H., Kim S-I., Song K-S. and Song K-S., Arch. Pharm. Res., 24, 292 (2001).
• 16. Yoshimoto T., Walter R. and Tsuru D., J. Biol. Chem., 255,4786 (1980