Replacement of an Anomeric Hydroxyl Group by a Halogen Atom Using PdCl2/Et3SiH/Halogen Source System

• Autorzy: Hassan H. , El-Husseiny A. H. F.
• Języki publikacji: EN

Abstrakty

EN

The anomeric hydroxyl group of perbenzylated and peracetylated carbohydrates can be stereoselectively replaced by a bromine or iodine atom using palladium dichloride, triethylsilane and carbon tetrabromide and/or iodine at room temperature. To illustrate the synthetic potential of this novel method, some models of O- and C-glycosides are reported. Reduction of sugar halide using excess of triethylsilane was not successful.

Słowa kluczowe

EN

glycosyl donor; palladium; anomers; reduction

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2001
• Tom: Vol. 75, nr 6
• Strony: 803--811
• Opis fizyczny: Bibliogr. 23 poz., rys.

Twórcy

autor

Hassan H.

• Chemistry Department, Faculty of Science, Alexandria University, P.O 426 Ibrahimia, 21321-Alexandria, Egypt

autor

El-Husseiny A. H. F.

• Chemistry Department, Faculty of Science, Alexandria University, P.O 426 Ibrahimia, 21321-Alexandria, Egypt

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