Wirtualne badanie DSC-MRI mózgu - część 1: krzywe stężenia znacznika charakterystyczne dla różnych rejonów mózgu

• Autorzy: Lipiński S. , Kalicka R.

Warianty tytułu

EN

Virtual DSC-MRI brain research - part 1: tracer concentration curves characteristic for different brain regions

• Języki publikacji: PL

Abstrakty

PL

W pracy pokazano metodę tworzenia typowych krzywych stężenia znacznika w badaniu DSC-MRI, charakterystycznych dla trzech obszarów mózgu: substancji białej, szarej oraz naczyń krwionośnych. Na podstawie zależności między wybranymi deskryptorami perfuzji krzywe pomiarowe z rzeczywistego badania DSC-MRI zaklasyfikowano do każdego z tych trzech zbiorów i uśredniono, uzyskując typowe przebiegi zmian stężenia znacznika dla każdego z wyróżnionych obszarów.

EN

DSC-MRI (Dynamic Susceptibility Contrast - Magnetic Resonance Imaging) research is one of the most modern methods for diagnosis of brain diseases, such as: tumours, stroke, epilepsy, migraine and dementia [1, 2]. For this purpose, the so called perfusion parameters are defined, of which the most commonly used are: CBF (Cerebral Blood Flow), CBV (Cerebral Blood Volume) and MTT (Mean Transit Time) [5, 6]. There are many approaches to determine these parameters [4, 5, 8, 9], but regardless of the approach, there is a problem with a quality assessment of particular methods, as well as comparison with others. The paper shows the method of creating typical curves from DSC-MRI studies, characteristic for different regions of the brain: the grey and white matter, and for blood vessels. Using perfusion descriptors, curves were classified into three sets, which after averaging them, gave the model curves for each of the three regions of the brain (Fig. 2). The method was verified by comparing the perfusion parameters calculated on the basis of the obtained characteristic curves with the values presented in the literature (Tab. 1). In Section 2 of the paper the way of using the created curves is shown, i.e. creating a virtual DSC-MRI brain study. Introduction of pathology to the created study and then its identification with use of different methods will allow comparing their effectiveness and quality of created perfusion maps.

Słowa kluczowe

PL

badania DSC-MRI mózgu; deskryptory perfuzji; krzywa charakterystyczna stężenia znacznika

EN

DSC-MRI brain research; perfusion descriptors; characteristic tracer concentration curves

• Wydawca: Wydawnictwo PAK
• Czasopismo: Pomiary Automatyka Kontrola
• Rocznik: 2012
• Tom: R. 58, nr 12
• Strony: 1129--1132
• Opis fizyczny: Bibliogr. 27 poz., rys., tab., wzor

Twórcy

autor

Lipiński S.

autor

Kalicka R.

• Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauk Technicznych, Katedra Elektrotechniki, Energetyki i Automatyki, ul. Oczapowskiego 11, 10-736 Olsztyn,

Bibliografia

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