A transient state analysis of gas exchange in a human body

• Autorzy: Polak A. G. , Wysoczyński D. , Mroczka J.

Warianty tytułu

PL

Analiza stanów przejściowych wymiany gazowej w ciele człowieka

• Języki publikacji: EN

Abstrakty

EN

A computational model of gas exchange in a human body was investigated in the transient states to determine its sensitivity to the model parameters and, on this basis, to analyse the possibility of their indirect measurement. The results indicate that some of the parameters influence the outputs significantly in the transient state and that registration of four output signals increases their number. The precision of estimation is disturbed, however, by the correlation between the output sensitivities to the model parameters. This research should be prolonged to analyse the measurement possibilities and accuracy in case of known diseases when additional information about the underlying pathological processes eliminates some of the disturbing correlations.

PL

Przeprowadzono badania symulacyjne komputerowego modelu wymiany gazowej u człowieka w warunkach stanów nieustalonych, których celem było wyznaczenie wrażliwości modelu na poszczególne jego parametry oraz analiza możliwości pośredniego ich pomiaru. Wyniki symulacji pokazują, że wartości niektórych parametrów mają istotny wpływ na wyjścia modelu w stanach nieustalonych, a rejestracja czterech sygnałów wyjściowych zwiększa ich liczbę. Czynnikiem zakłócającym dokładność pomiarów jest wysoka korelacja między większością wektorów wrażliwości. Prezentowane badania wstępne będą kontynuowane w celu przeanalizowania możliwości i dokładności pomiaru w przypadku konkretnych jednostek chorobowych, kiedy to znajomość zachodzących procesów patologicznych wyeliminuje niektóre z niepożądanych korelacji.

Słowa kluczowe

EN

gas exchange; computational model; transient state; sensitivity analysis; parameter selection

PL

wymiana gazowa; model obliczeniowy; stan nieustalony; analiza czułości; dobór parametru

• Wydawca: Komitet Metrologii i Aparatury Naukowej PAN
• Czasopismo: Metrology and Measurement Systems
• Rocznik: 2004
• Tom: Vol. 11, nr 4
• Strony: 321--332
• Opis fizyczny: Bibliogr. 26 poz., rys., tab., wykr.

Twórcy

autor

Polak A. G.

• Wrocław University of Technology, Chair of Electronic and Photonic Metrology

autor

Wysoczyński D.

• Wrocław University of Technology, Chair of Electronic and Photonic Metrology

autor

Mroczka J.

• Wrocław University of Technology, Chair of Electronic and Photonic Metrology

Bibliografia

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