Sol-gel coated fiberoptic applicator for photodynamic medicine - optical and AFM characterization

• Autorzy: Kopaczyńska M. , Hołowacz I. , Ulatowska-Jarża A. , Buzalewicz I. , Podbielska H.
• Języki publikacji: EN

Abstrakty

EN

The application of spectroscopic study, microscopic and AFM imaging for examination of fiberoptic applicators is presented. The potential carriers of photoactive agents for photodynamic medicine in form of sol-gel coatings of fiberoptic applicators, are proposed. Optical and morphological properties of the proposed sol-gel coatings doped with photosensitizer Photolon, are characterized. The influence of pH and oxygen changes on entrapped Photolon properties, was examined, as well. The morphology of the applicator coating was examined by using atomic force microscopy. The light distribution from an applicator was studied by means of computer aided image analysis.

Słowa kluczowe

EN

photosensitizer; photolon; biocarrier; fiberoptic applicator; photodynamic therapy (PDT)

PL

fotosensybilizator; fotolon; bionośnik; aplikator światłowodowy; terapia fotodynamiczna (PDT)

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2012
• Tom: Vol. 32, no. 1
• Strony: 41--50
• Opis fizyczny: Bibliogr. 32 poz., rys., wykr.

Twórcy

autor

Kopaczyńska M.

autor

Hołowacz I.

autor

Ulatowska-Jarża A.

autor

Buzalewicz I.

autor

Podbielska H.

• Institute of Biomedical Engineering and Instrumentation Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland,

Bibliografia

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