Peripheral and central afferent input to the lumbar cord

• Autorzy: Minassian K. , Persy I. , Rattay F. , Dimitrijevic M.R.
• Języki publikacji: EN

Abstrakty

EN

It has been previously demonstrated that epidural stimulation of the posterior lumbar cord can activate the Lumbar Locomotor Pattern Generator (LLPG) and induce stepping-like movements in complete spinal cord injured subjects. In these studies, the subjects were lying in a supine position and afferent feedback input from the lower limbs was minimized. The present paper demonstrates the interaction between induced LLPG activity and manually assisted treadmill stepping in paralyzed subjects. Epidural stimulation applied at frequencies of 20-50 Hz during treadmill-stepping enhanced the responsiveness of the spinal circuits to proprioceptive feedback in generating stepping-like motor patterns. We suggest that the spinal lumbar networks can integrate and interpret both, the stimulus-evoked tonic input with a "central" code and the proprioceptive feedback input in order to generate effective loco motor patterns.

Słowa kluczowe

EN

spinal cord injury; assised treadmill-stepping; epidural spinal cord stimulation; posterior roots; motor output; locomotion

PL

uraz rdzenia kręgowego; rdzeń kręgowy; czynność ruchowa

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2005
• Tom: Vol. 25, no. 3
• Strony: 11--29
• Opis fizyczny: Bibliogr. 15, rys., tab.

Twórcy

autor

Minassian K.

• Ludwig Boltzmann Institute for Electrical Stimulation and Physical Rehabilitation, Vienna, Austria

autor

Persy I.

• TU-BioMed Association for Biomedical Engineering, Vienna University of Technology, Vienna, Austria

autor

Rattay F.

• TU-BioMed Association for Biomedical Engineering, Vienna University of Technology, Vienna, Austria

autor

Dimitrijevic M.R.

• Departament of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, Texas, USA; University Institute for Clinical Neurophysiology, Clinical Center of Ljubljana, Slovenia

Bibliografia

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