Transcranial magnetic stimulation: twenty years of stimulating the human motor cortex in health and disease

• Autorzy: Rothwell J. C.
• Języki publikacji: EN

Abstrakty

EN

In the motor system, transcranial magnetic stimulation (TMS) has proved an invaluable tool to study the organisation and interaction of the cortical motor areas. In this review I describe some of the ways in which TMS has been used to map out the major topographical features of the motor output and to test how these change in response motor learning or after peripheral (e.g. amputation) or central (e.g. stroke) injury. More recent work has shown that longer periods of repeated TMS involving several hundred to a thousand pulses can lead to lasting changes in motor cortex excitability that are thought to involve changes in the efficacy of intracortical synapses equivalent to LTP and LTP in slice preparations. These are accompanied by changes in the rate of motor learning and are presently being trialled as potential treatments to speed recovery from stroke.

Słowa kluczowe

EN

transcranial magnetic stimulation; TMS; repetitive TMS; virtual lesion; plasticity; stroke rehabilitation; cortical mapping

PL

stymulacja przezczaszkowa; stymulacja magnetyczna; uszkodzenie wirtualne; udar mózgu

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2011
• Tom: Vol. 31, no. 2
• Strony: 81--91
• Opis fizyczny: Bibliogr. 22 poz., rys., wykr.

Twórcy

autor

Rothwell J. C.

• UCL Institute of Neurology, Queen Square, London WC1N3BG, UK,

Bibliografia

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