Image processing algorithm for cell force sensor with a micropillar patterned substrate

• Autorzy: Smolik W. T. , Święszkowski W. , Kurzydłowski K. J. , Bruinink A. , Danz N.
• Języki publikacji: EN

Abstrakty

EN

The paper presents an image analysis for cell force measurement using a patterned substrate surface. The cell forces are transduced to a hexagonal lattice of microcantilevers in the shape of cylindrical pillars installed on a substrate surface. The magnitude and direction of pillars deflection is measured optically by an analysis of transmission images of the substrate. The template matching is used for identification of the position of pillars. The hexagonal lattice of pillars is identified automatically and used as information about the reference rest position of the pillars. The elaborated algorithm was tested using simulated data. The first results using real images are presented.

Słowa kluczowe

EN

cell forces; cell motility; cell imaging; micro-patterned substrate; micropost array; image processing

PL

komórka; przetwarzanie obrazu; analiza obrazu

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2010
• Tom: Vol. 30, no. 3
• Strony: 49--64
• Opis fizyczny: Bibliogr. 20 poz., rys.

Twórcy

autor

Smolik W. T.

autor

Święszkowski W.

autor

Kurzydłowski K. J.

autor

Bruinink A.

autor

Danz N.

• Warsaw University of Technology, ul. Nowowiejska 15/19, 00-665 Warsaw, Poland,

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