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Języki publikacji
EN
Abstrakty
EN
In this paper an automatic system for measuring motor abilities of mice and the test results of two groups of control mice are presented. The system was designed for the benefit of experiments related to diagnostics of stroke neurological symptoms. Here we tested the validity of a system for monitoring long-term mobility of wild mice using software specifically designed for automated data gathering and analyses. The system analysed all data and filled the database with measured values characterizing the mobility of mice. Subsequent analysis revealed that there is no difference in two groups of control animals. The results indicate that this type of monitoring might constitute a reliable tool for examining neurological functions in laboratory animals.
Twórcy
  • Faculty of Electronics, Telecommunication and Informatics, Departament of Biomedical Engineering, Gdańsk University of Technology, ul. Gabriela Narutowicza 11/12, 80-952 Gdańsk, Poland, magda@biomed.eti.pg.gda.pl
Bibliografia
  • 1. Gorelick P.B.: The burden and management of TIA and stroke in government-funded healthcare programs. Am. J. Manag. Care. 2009, 15, 6 (Suppl), 177-184.
  • 2. O'Donnell M., Yusuf S.: Tackling the global burden of stroke: the need for large-scale international studies. Lancet Neurol. 2009, 8, 4, 306-307.
  • 3. Johnston S.C., Mendis S., Mathers C.D.: Global variation in stroke burden and mortality: estimates from monitoring, surveillance, and modelling. Lancet Neurol. 2009, 8, 4, 345-354.
  • 4. Di Carlo A.: Human and economic burden of stroke. Age Ageing 2009, 38, 1, 4-5.
  • 5. Warlow C.P., Dennis M.S., Van Gijn J., Hankey G.J., Sadercock P., Bamford J.M., Wardlaw J.: Stroke - a practical guide to management. Blackwell Science RRP, ISBN: 0-86542-876-3, 2008.
  • 6. Torbey M.T., Selim M.H. (Eds): The stroke book. (ISBN-13: 9780521671606), Cambridge University Press, 2007.
  • 7. Wardlaw J.M., Murray V., Berge E., Del Zoppo G.J.: Thrombolysis for acute ischaemic stroke. Cochrane Database Syst Rev. 2009, 4, CD000213.
  • 8. Bland J.M., Altman D.G.: Statistical methods for assessing agreement between two methods of clinical measurements. Lancet 1986, 8, 307-310.
  • 9. Tillerson J.L., Miller G.W.: Grid performance test to measure behavioural impairment in the MPTP-treated-mouse model of parkinsonism. J. Neurosc. Meth. 2003, 123, 189-200.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPZ1-0059-0015
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