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Abstrakty
The relationship between Forced Expiratory Volume in one second (FEV1) and the Forced Vital Capacity (FVC) is intensively used in diagnosing because of its quantitative description with the index FEV1/FVC. There is not such index for the relationship between airflows (Peak Expiratory Flow (PEF) and Maximal Expiratory Flow at xx% of FVC (MEFxx, where xx = 75, 50, 25%)). Our aim was to describe that relationship quantitatively with the angle alfa between the 4-dimensional vector F = [PEF, MEF75, MEF50, MEF25] and the plane determined by two reference vectors: the mean of such vectors for the young and elderly. The reference vectors were found with data for 1,120 males and 1,625 females - Polish (white) population, healthy, never-smoking, aged 18 - 85 yrs, who performed a technically adequate spirometry maneuver. Upper Limit of Normal (ULN) was determined with the linear regression of the 5th percentiles of alfa on age (0.074*age + 2.76). Such an ULN seems to well indicate both improper examination and non-healthy persons.
Wydawca
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Tom
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17--25
Opis fizyczny
Bibliogr. 12 poz., rys., tab., wykr.
Twórcy
autor
autor
- Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland, tgolczewski@ibib.waw.pl
Bibliografia
- 1. Mead J., Turner J.M., Macklem P.T., Little J.B.: Significance of the relationship between lung recoil and maximum expiratory flow. J. Appl. Physiol. 1967, 22, 95-108.
- 2. Pride N.B., Permutt S., Riley R.L., Bromberger-Barnea B.: Determinants of maximum expiratory flow from the lungs. J. Appl. Physiol. 1967, 23, 646-662.
- 3. Gólczewski T., Darowski M.. Virtual respiratory system for education and research: simulation of expiratory flow limitation for spirometry, Int. J. Artif. Organs 2006, 29, 961-972.
- 4. Tiffeneau R., Pinelli A.: Air circulant et air captif dans l'exploration de la fonction ventilatoire pulmonaire. Paris Med. 1947, 133, 624-631.
- 5. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease Updated 2003: NHLBI/WHO Workshop. National Heart, Lung, and Blood Institute, World Health Organization. Based on an April 1998 American Thoracic Society. Am. J. Respir. Crit Care Med. 1995, 152, 1107-1136.
- 6. Hardie J.A., Buist A.S., Vollmer W.M., Ellingsen I., Bakke P.S., Mørkve O.: Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers. Eur. Respir. J. 2002, 20, 1117-1122.
- 7. Falaschetii E., Laiho J., Primatesa P. at al.: Prediction equations for normal and low lung function from the Health Survey for England. Eur. Respir. J. 2004, 23, 456-463.
- 8. www.goldcopd.org Global Strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease, 2006.
- 9. Gólczewski T., Krajewski A.: A vector based approach to age-related changes of Doppler velocity waveforms in the brachial artery, Ultrasound Med. Biol., 1987, 13, 15-18.
- 10. Gólczewski T.: A method of presentation of chosen hemodynamical quantities as vectors in L2(T) space for biological state differentiating - Analysis of arterial blood flow waveform for estimation of ageing advance. Prace IBIB PAN, 1994, 38 [in Polish].
- 11. Healy M.J.R., Rasbash J., Yang M.: Distribution-free estimation of age-related centiles. Ann. Hum. Biol. 1998, 15, 17-22.
- 12. Standardized lung function testing. Official statement of the European Respiratory Society [see comments]. Eur. Respir. J. Suppl 1993, 16, 1-100.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPZ1-0045-0019