Microsystems in biochemical diagnosis

• Autorzy: Torbicz W. , Pijanowska D.
• Języki publikacji: EN

Abstrakty

EN

Semiconductor technology gives possibilities of miniaturization of chemical sensors and biosensors and integration of them with the required microfluidics systems and/or electronics to create a micro analytical system called the micro-TAS or the lab-on-a-chip. One of the very important groups of potentiometric chemical sensors is the ion sensitive field effect transistors (ISFETs). In this paper, the results of our research on development of the electrochemical type biosensors and microreactors for biomedical applications, including immobilization of bioreceptors onto the sensing part of biosensors and microreactors and their implementation into microsystems, are presented.

Słowa kluczowe

EN

(bio)chemical sensors; biosensors; micro analytical systems; lab-on-a-chip

PL

czujnik biochemiczny; czujnik biologiczny; mikrosystem

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2007
• Tom: Vol. 27, no. 1-2
• Strony: 33--43
• Opis fizyczny: Bibliogr. 34 poz., rys., tab., wykr.

Twórcy

autor

Torbicz W.

autor

Pijanowska D.

• Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland,

Bibliografia

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• 3. Torbicz W.: Theory and properties of field effect transistors as chemical and biochemical sensors (in Polish), Wrocław, Ossolineum, 1988.
• 4. Pijanowska D.G.: Analysis of factors determining parameters of ion sensitive field effect transistors as the sensors of biochemical quantities, Warszawa: Prace IBIB PAN, 1996, 46.
• 5. Pijanowska D.G., Torbicz W., Jaroszewicz B., Grabiec P.: Czujniki pehametryczne typu p-well ISFET, Elektronizacja, 2003, 6, 26-30.
• 6. Sobczyńska D., Torbicz W.: ZrO2 gate.pH sensitive field effect transistor, Sens. Actuators, 1984, 6, 93-105.
• 7. Sobczyńska D., Torbicz W., Olszyna A. and Włosiński W.: Borazon gate pH sensitive field effect transistor, Analyt. Chim. Acta, 1985, 171, 357-361.
• 8. Torbicz W., Oxides of the titanium family metals as membranes in pH ISFETs, Lecture Notes of the ICB Seminar on Biomeasurements, Jablonna, 1990, 3, 328-344.
• 9. Pijanowska D. and Torbicz W.: Long-term stability of Si3N4, A12O3 and Ta2O5 gate pH-ISFETs Proc. of SPIE, 1995, 2634, 210-214.
• 10. Krzyśków A., Pijanowska D., Kruk J.: Controller of the operation point of the chemical sensor of the ion sensitive field effect transistor ISFET type, Polish Patent, 1996, 178242.
• 11. Chung W.Y., Krzyśków A., Lin Y.T., Pijanowska D.G., Yang C.H., Torbicz W.: Electronic circuit for ion sensor, US Patent, 2005, US 6,906,524 B2.
• 12. Chung W.Y., Yang C.H., Pijanowska D.G., Krzyśków A., Torbicz W.: ISFET interface circuit embedded with noise rejection capability, Electron. Letters, 2004,40 (18), 1115-1116.
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• 14. Dawgul M., Jaźwiński J., Koszur J., Brzózka Z., Torbicz W.: Development of an intermediate hydrogel layer for chemically modified FET based on Si3N4, Proc. of Eurosensors XI Conference, Warsaw, 1997, 1275-1278.
• 15. Starodub N.F., Torbicz W, Pijanowska D., Starodub V.M., Kanjuk M.I., Dawgul M.: Optimisation methods of enzyme integration with transducers for analysis of irreversible inhibitors, Sens. Actuators B, 1999,58,420-426.
• 16. Dawgul M., Pijanowska D.G., Krzyśków A., Kruk J., Torbicz W.: An influence of polyHEMA gate layer on properties of ChemFETs, Sensors, 2003, 3, 146-159.
• 17. Dawgul M.: Semiconductor sensors and biosensors based on ammonium ion detection (in Polish), Thesis, 2003, Warsaw: IBBE PAS.
• 18. Pijanowska D.G., Torbicz W: pH-ISFET based urea biosensor, Sens. Actuators B, 1997, 44, 370-376.
• 19. Brzózka Z., Dawgul M., Pijanowska D., Torbicz W: Durable NH4+-sensitive CHEMFET, Sens. Actuators B, 1997,44, 527-531.
• 20. Pijanowska D. G., Luboch E., Biernat J.F., Dawgul M., TorbiczW.: Na+-selective ChemFETs based on novel ionophore: bis(phenylbenzo)-13-azocrown-5, Sens. Actuators B, 1999, 58, 384-388.
• 21. Pijanowska D.G., Torbicz W.: The pH-detection of triglycerides, Sens. Actuators B, 2001, 78, 263-266.
• 22. Kazimierczak B., Baraniecka A., Pijanowska D., Dawgul M., Kruk J., Krzyśków A., Torbicz W: Immunological reactions in potentiometric sensors, Proc of SPIE, 2002, 4887, 137-140.
• 23. Pijanowska D.G., Jaffrezic-Renault N., Martelet C., Torbicz W.: ISFET type urea biosensors for biomedical applications, Recent Research Developments in Electroanalytical Chemistry, Chapter 3, 7-20, Trivandrum, India: Transworld Research Network, 2001.
• 24. Pijanowska D.G., Dawgul M., Torbicz W.: Comparison of urea determination in biological samples by EnFETs based on pH and pNH4 detection, Sensors, 2003, 3,160-165.
• 25. Dawgul M., Trybun T., Pijanowska D.G., Torbicz W.: EnFET for urea determination in biological fluids using ammonium ion detection, Proc. of SPIE, 2003, 5124, 154-161.
• 26. Starodub N.F., Torbicz W., Pijanowska D., Kanjuk N., Dawgul M., Ternovoj A.S.: Phosphororganic pesticide control in some vegetables by enzymatic sensors based on ISFETs, Proc. of Eurosensors X Conference, Leuven, 1996, 925-928.
• 27. Starodub N.F., Torbicz W., Starodub V., Kanjuk N., Dawgul M., Pijanowska D., Ternovoj K.S.: Control of heavy metal ion level in some vegetables by enzymatic sensors based on the ISFETs, Proc. of Eurosensors XI Conference, Warsaw, 1997, 1233-1236.
• 28. Bergveld P., Olthuis W., Sprenkels A.J., Pijanowska D.G., van der Linden H., Bohm S.: Microdia-lysis based lab-on-a-chip, applying a generic MEMS technology, w: Integrated analytical systems, Ch.l5; Seria: Comprehensive Analytical Chemistry XXXIX, ELSEVIER Sc. B.V., Amsterdam, 2003, 625-663.
• 29. Torbicz W, Pijanowska D.G., Remiszewska E.: Bioanalytical and Medical Trends in Sensor Applications, Micro-bioreactor-sensor systems for monitoring of biochemical parameters, Technology and Health Care 2001, 9/1-2, 91-93.
• 30. Pijanowska D.G., Remiszewska E., Pederzolli C., Lunelli L., Vendano M., Canteri R., Dudziński K., Kruk J., Torbicz W.: Surface modification for microreactors fabrication, Sensors, 6,2006, 370-379.
• 31. Recommendations for immobilization of enzymes on EUPERGIT®, EUP_MMO/E, 2004/08, www.roehm.com.
• 32. Pijanowska D.G., Sprenkels A.J., van der Linden H., Olthuis W., Bergveld P. and van den Berg A.: A flow-through potentiometric sensor for an integrated microdialysis system, Sens. Actuators B, 2004, 103, 350-355.
• 33. Pijanowska D.G., Sprenkels A.J., van der Linden H., Olthuis W., Bergveld P. and van den Berg A.: A flow-through potentiometric sensor for an integrated microdialysis system, Sens. Actuators B, 2004, 103,350-355.
• 34. Pijanowska D.G., Sprenkels A.J., Olthuis W., Bergveld P.: A flow-through amperometric sensor for micro analytical systems, Sens. Actuators B, 2003, 91, 98-102.