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Abstrakty
EN
T-wave alternans (TWA), which has recently been detected at the micro-volt level, is a non-invasive marker of the vulnerability to ventricular arrhythmia. The aim of this study was to compare the presently used TWA detection methods and to determine the ECG signal acquisition and processing conditions ensuring the TWA detection at its lowest possible level. The results of the evaluation and comparison of seven methods are presented. The ECG signal analysis was performed in the time and frequency domain. The differential and correlation methods were applied as the time domain methods. The complex demodulation method and methods based on the FFT and Karhunen-Loeve transform were tested as the frequency domain methods. The T-wave alternans markers were measured in 28 patients, and the results were compared. The usefulness of TWA detection methods has been demonstrated to dependant on the signal properties, such as the nonstationarity of TWA and the level of noise. Strong correlation between the magnitude of the T-wave alternans and ventricular repolarization time is described. A new, spectral methods is proposed.
Twórcy
autor
  • Institute of Radioelectronics, Warsaw University of Technology, Nowowiejska 15/19, 00-665 Warsaw, Poland
  • Institute of Radioelectronics, Warsaw University of Technology, Nowowiejska 15/19, 00-665 Warsaw, Poland
  • Postgraduate Medical School, Grochowski Hospital, Warsaw, Poland
  • Institute of Cardiology, Warsaw, Poland
Bibliografia
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  • [2] Smith J.M., Clancy E.A., Valeri C.R., Ruskin J.N., Cohen R.J..: Electrical alternans and cardiac electrical instability, Circulation 1988,77, 110-121.
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  • [4] Mayer C.R., Keiser H.: Electrocardiogram baseline noise and removal using cubic splines and state-space computation techniques, Computers and Biomedical Research 1977, 10, 459-470.
  • [5] Bazett H.C.: An analysis of the time-relation od electrocardiogram, Heart 1920, 7, 353-370.
  • [6] Karczmarewicz S., Kułakowski P., Janusek D., Buczkowski T., Janusek P., Kociszewska J., Soszyńska M., Cermużyński L.: „The new, non-rate-dependent algorithm of T-wave identification for time-domain analysis of T-wave alternans”, 11th International Congress Cardiostim '98, (Nice, June 17-20, 1998), Proceedings, 174/PW, p. 315.
  • [7] Zaręba W., Badilini F., Moss A.J.: Automatic detection of non-visible T-wave alternans from three-channel Holter recordings, J. Am. Coll. Cardiol 1995, 25, Suppl.
  • [8] Rosenbaum D., Jackson L., Smith J., Garan H., Ruskin J., Cohen R.: Electrical alternans and vulnerability to ventricular arrythmias, N. Engl. J. Med 1994, 330, 235-241.
  • [9] Nearing B.D., Huang A.H., Verrier R.L.: Dynamic tracking of cardiac vulnerability by complex demodulation of the T-wave, Science 1991, 437-440.
  • [10] Laguna P, Moody G.B. And Mark R.: Repolarization alternans detection using the KL transform and the beatquency spectrum, Computers in Cardiology, IEEE Computer Society Press 1996, 673-676.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPZ1-0011-0022
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