Polypropylene surface modified hollow fibers for immunoisolation of cells

• Autorzy: Granicka L. H. , Chwojnowski A. , Kawiak J.
• Języki publikacji: EN

Abstrakty

EN

Membranes preventing the tissue overgrowth as well as toxic influence of the environment on cells encapsulated within them were elaborated. The permiselective polypropylene hollow fibers were modified using different methods of silanization, and the effect of silanization on the membrane transport properties as well as on the tissue overgrowth was assessed, in the light of their perspective application in encapsulation of the cells. The membrane's pressure silanization has been found to result in obtaining membranes allowing to decrease and/ or delimit the diffusive transport through the membrane of large solutes without a simultaneous transport change for small solutes. The applied different types of membrane's silanization allowed to avoid a massive tissue overgrowth during the implantation. The membranes have been found to comply with the requirements for membranes applied in immunoisolation.

Słowa kluczowe

EN

hollow fibers; silanization; diffusive transport; implantation

PL

silanizacja; transport dyfuzyjny; implantacja

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2004
• Tom: Vol. 24, no. 2
• Strony: 59--67
• Opis fizyczny: Bibliogr. 20 poz., rys., tab., wykr.

Twórcy

autor

Granicka L. H.

• Institute of Biocybernetics and Biomedical Engineering, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland

autor

Chwojnowski A.

• Institute of Biocybernetics and Biomedical Engineering, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland

autor

Kawiak J.

• Institute of Biocybernetics and Biomedical Engineering, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland; Medical Center of Postgraduate Education, Departament of Clinical Cytology, Warsaw, Poland

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