The influence of ventilatory support on coronary flow and oxygen consumption in different circulatory conditions

• Autorzy: De Lazzari C. , Darowski M. , Ferrari G. , Mimmo R. , Guaragno M. , Tosti G.
• Języki publikacji: EN

Abstrakty

EN

The aim of this work is to predict the influence of mechanical ventilation on cardiac output, coronary flow and left ventricular myocardial oxygen consumption in different circulatory conditions. To study this interaction we used a computer simulator of human cardiovascular system in which lumped parameters models were used to reproduce the circulatory phenomena in terms of pressure and volume relationships. Variable elastance models reproduce the Starling's law of the heart, for each ventricle. In the study the left ventricular elastance assumed two different values. Symetric arterial resistance was changed during the simulation. The influenece of mechanical ventilation was introduced by positive mean thoracic pressure. Positive thoracic pressure, changes of peripheral resistance and different ventricular elastance values have a significant influence on cardiac output, coronary flow and myocardial oxygen consumption.

Słowa kluczowe

EN

ventilatory support; hemodynamics; coronary flow; oxygen consumption

PL

wspomaganie oddechowe; hemodynamika; przepływ wieńcowy

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2003
• Tom: Vol. 23, no. 1
• Strony: 103--110
• Opis fizyczny: Bibliogr. 10 poz., rys., tab., wykr.

Twórcy

autor

De Lazzari C.

• Instituto di Tecnologie Biomediche CNR, Reparto di Ingegneria Cardiovascolare, Roma, Italia

autor

Darowski M.

• Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland

autor

Ferrari G.

• Instituto di Tecnologie Biomediche CNR, Roma, Italia

autor

Mimmo R.

• Instituto di Tecnologie Biomediche CNR, Roma, Italia

autor

Guaragno M.

• Instituto di Tecnologie Biomediche CNR, Roma, Italia

autor

Tosti G.

• Instituto di Tecnologie Biomediche CNR, Roma, Italia

Bibliografia

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• [5] Mantero S., Pietrabissa R., Fumero R.: The coronary bed and its role in the cardio vascular system: a review and an introductory single-branch model. J. Biomed Eng. 1992, 14, 109-116.
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• [7] De Lazzari C., Darowski M., Ferrari G Clemente F., Guaragno M.: Ventricular energetics during mechanical ventilation and intraaortic balloon pumping — Computer simulation. Journal of Medical Engineering & Technology 2001, 25, 103-111.
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