On the design of biodegradable hydrogels both thermosensitive and pH sensitive

• Autorzy: Wang B. , Guo Y. , Hu G.
• Języki publikacji: EN

Abstrakty

EN

A Pluronic oligo(?-caprolactone) block copolymer has been synthesized by ring opening polymerization of ?-caprolactone monomers in the presence of poly(ethylene oxide)-poly(propylene oxide) -poly(ethylene oxide) triblock copolymers, using stannous octoate as a catalyst, and then the block copolymer was terminated with an acryloyl group. A novel biodegradable pH- and temperature sensitive hydrogel has been fabricated by free radical copolymerization of diacylated macromer-methacrylic acid aqueous solution initiated by a redox initiator. The structures of products were characterized by the Fourier transform infrared spectroscopy. Variations of the equilibrium swelling ratio in various environmental solutions confirmed the pH- and temperature sensitivity of hydrogel, which were affected by the MAA content.

Słowa kluczowe

EN

biodegradable hydrogel; pH sensitivity; temperature sensitivity

• Wydawca: De Gruyter
• Czasopismo: Materials Science Poland
• Rocznik: 2010
• Tom: Vol. 28, No. 1
• Strony: 207--215
• Opis fizyczny: Bibliogr. 15 poz.

Twórcy

autor

Wang B.

autor

Guo Y.

autor

Hu G.

• Institute of Macromolecules and Bioengineering North University of China Taiyuan 030051 China

Bibliografia

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