Syntheses and characterization of pH-sensitive hydrogel from poly(.gamma.-glutamic) acid

• Autorzy: Yao B. , Yang C. , Zhang K. , Ni C. , Song H. , Ni Z. , Chen M.
• Języki publikacji: EN

Abstrakty

EN

Novel pH-sensitive hydrogels were prepared through crosslinking of poly(.gamma.-glutamic) acid (.gamma.-PGA) by using 1,4-butanediol diglycidyl ether as a cross-linker, tetraethylammonium bromide as a catalyst, and reacting in DMSO. The dependence of the swelling ratio of the hydrogels on pH values, ionic strength and cross-linking degree was investigated. It was found that the pH-sensitive range was clearly extended through introducing multiple hydrogen bonds to the hydrogel network during the preparation. The swelling ratios of ?-PGA hydrogels increased with the increase in pH of the aqueous solution from 2 to 9. The swelling of the .gamma.-PGA hydrogels was firstly controlled by the ionization of carboxyl groups in the hydrogels within the pH range from 2 to 5, and then controlled by breaking of the multiple hydrogen bonds in the hydrogels within the pH range from 5 to 9. The swelling ratios of .gamma.-PGA hydrogels were also strongly dependent on the ionic strength of the medium and cross-linking degree of the hydrogels. Increasing the ionic strength and the crosslinking degree resulted in a decrease in the swelling ratio of the hydrogels.

Słowa kluczowe

EN

poly(.gamma.-glutamic) amid; pH-sensitive hydrogel; crosslinking; swelling

• Wydawca: De Gruyter
• Czasopismo: Materials Science Poland
• Rocznik: 2009
• Tom: Vol. 27, No. 1
• Strony: 319--327
• Opis fizyczny: Bibliogr. 20 poz.

Twórcy

autor

Yao B.

autor

Yang C.

autor

Zhang K.

autor

Ni C.

autor

Song H.

autor

Ni Z.

autor

Chen M.

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