Bioactive glass coatings

• Autorzy: Sindut R. , Cholewa-Kowalska K. , Najman J. , Łączka M. , Karpov M. , Osyczka A. M. , Leboy P.
• Konferencja: Sol-Gel Materials Research, Technology, Applications SGM'04, 6-11 june 2004
• Języki publikacji: EN

Abstrakty

EN

Four kinds of gel-derived materials of the CaO-P2O5-SiO2 (S2, II, I, A2) system were obtained in the form of thin coatings on microscope slides. The obtained materials differed from each other in the ratio of the basic components (CaO and SiO2). The coatings were characterised with regard to the state of the surface as well as to the phase composition of the materials. In order to determine any bioactive properties of the gel-derived coatings in vitro, tests in simulated body fluid (SBF) were made and biochemical examinations using cultured human marrow stromal cells (hMSC) were conducted. It was found that surface crystallisation of hydroxyapatite (HAp) indicating the bioactivity of the material occurred in SBF only in the case of A2 coatings, which are characterised by the highest ratio of CaO:SiO2. Tests with hMSC showed that the A2 biomaterial promotes both the osteogenesis and remodelling of bone (osteoclastogenesis).

Słowa kluczowe

EN

biomaterials; bioactivity; sol-gel method

• Wydawca: De Gruyter
• Czasopismo: Materials Science Poland
• Rocznik: 2005
• Tom: Vol. 23, No. 1
• Strony: 123--136
• Opis fizyczny: Bibliogr. 11 poz.

Twórcy

autor

Sindut R.

• AGH-University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Glass Technology and Amorphous Coating, 30-059 Cracow, Poland

autor

Cholewa-Kowalska K.

• AGH-University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Glass Technology and Amorphous Coating, 30-059 Cracow, Poland

autor

Najman J.

• Cracow University of Technology, Faculty of Chemical Engineering and Technology, Cracow, Poland

autor

Łączka M.

• AGH-University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Glass Technology and Amorphous Coating, 30-059 Cracow, Poland

autor

Karpov M.

• University of Pennsylvania, Philadelphia, 19104 PA, USA

autor

Osyczka A. M.

• University of Pennsylvania, Philadelphia, 19104 PA, USA

autor

Leboy P.

• University of Pennsylvania, Philadelphia, 19104 PA, USA

Bibliografia

• [1] HENCH L.L., Am. Ceram. Soc. Bull., 77 (1998), 67.
• [2] HENCH LL., J. Am. Ceram. Soc., 74 (1991), 1487.
• [3] KOKUBO T., KUSHITANI H., OHTSUKI C., SAKKA K., YAMAMURO T., J. Mater. Sci. Mater. Med., 3, (1992), 78.
• [4] LI.R., CLARK A.E., HENCH LL. J. Appl. Biomat., 2 (1991), 231.
• [5] LACZKA M., CHOLEWA-KOWALSKA K., LACZKA-OSYCZKA A.M., TWORZYDLO M., TURYNA B., J. Biomed. Mat. Res., 52 (2000), 601.
• [6] DISLICH H., J. Noncryst. Sol., 73 (1985), 599.
• [7] SAKOU T., Bone, 22 (1998), 591.
• [8] LACZKA-OSYCZKA A.M., LACZKA M., KASUGAI S., OHYA K., J. Biomed. Mat. Res., 42 (1998), 433.
• [9] SANTOS E.M., RADIN S., SHENKER B.J., SHAPIRO I.M., DUCHEYNE P., J. Biomed. Mat. Res., 41 (1998), 87.
• [10] KOKUBO T., J. Noncryst. Sol., 120 (1990), 138.
• [11] DUCHEYNE P., QIU Q., Biomaterials, 20 (1999), 2287.