Bone remodeling and bone adaptation

• Autorzy: Petrtyl M. , Danesova J.
• Języki publikacji: EN

Abstrakty

EN

Bone remodelling is a very complicated process that can be characterised as close relationship of biomechnical effects and biomechanical reactions. It is not possible to give an exact definition of the bone remodeling if we take into consideration the aspects related merely to biomechanics or to biochemistry. Biomechanical processes in a remodelled bone tissue depend on the dominant force and moment effects or on the stress and strain state of the tissue. The stress (strain) tensors initiate and govern the rate of biochemical remodelling processes. The paper presented deals with fundamental stoichiometric equations of bone remodelling, kinetic equations of remodelling and rate constants of remodelling. The rates of bone remodelling depend on mechanical effects or on stress (strain) tensors. The spherical stress tensor controls the rate of biomechanical remodelling reactions, while the deviator of a stress (strain) tensor initiates biomechanical reactions. The micro-strains cause the flow of a liquid in the extra-celluar space of osteocytes and initiate the receptor activity of integrins A,B, The micro-strains of a mineralised matrix and the flow of an extra-cellular liquid result, for example in the production of prostaglandin E2 and in the subsquent resorption of a bone tissue.

Słowa kluczowe

EN

bone remodeling; stoichiometric equations; kinetic equations; stress; strain; rate of remodelling; osteoclasts; osteoblasts; osteoid; osteocyte; integrin

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Acta of Bioengineering and Biomechanics
• Rocznik: 1999
• Tom: Vol. 1, nr 1
• Strony: 107--116
• Opis fizyczny: Bibliogr. 32 poz.,

Twórcy

autor

Petrtyl M.

autor

Danesova J.

• Czech Technical University in Prague, Faculty of Civil Engineering, Laboratory of Biomechanics and Biomaterial Engineering, Czech Republic