Application of the fluorescent fiber sensor for tumor cells quantification

• Autorzy: Bereś-Pawlik E.M. , Dybała F. , Michalski W. , Duś D.
• Języki publikacji: EN

Abstrakty

EN

In order to effectively treat or destroy tumor cells we should first detect and localize them. The paper presents a specially designed and constructed fluorescent fiber sensor of a very small size, meant for detecting live tumor cells. The sensor was used to measure the luminescent signal’s intensity coming from optically excited cells stained with propidium iodide. The intensity of the luminescent signal is proportional to the amount of pathologically changed cells. The obtained results confirm that it is possible to conduct definite and respectable measurements of luminescent signal’s intensity by means of the sensor, and at the same time these results allow us to identify tumor cells. The constructed sensor can be applied to the examination of tumor cells grown in vitro or taken from a living organism and examined in laboratory conditions. Because of the small size of the fiber probe it is also possible to use the sensor for detecting tumor cells inside the human body.

Słowa kluczowe

EN

fluorescent fiber sensor; tumor changes; examination of tumor changes

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Optica Applicata
• Rocznik: 2004
• Tom: Vol. 34, nr 1
• Strony: 87--92
• Opis fizyczny: Bibliogr. 4 poz., rys.

Twórcy

autor

Bereś-Pawlik E.M.

• Institute of Telecommunications and Acoustics, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland

autor

Dybała F.

• Department of Physics, Warsaw University of Technology, ul. Koszykowa 75, 00-662 Warszawa, Poland

autor

Michalski W.

• Institute of Telecommunications and Acoustics, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland

autor

Duś D.

• Institute of Immunology and Experimental Therapy, Polish Academy of Sciences (PAN),ul. Weigla 12, 53-114 Wrocław, Poland

Bibliografia

• [1] GRACZYK A., SOBCZYŃSKA J., STANOWSKI E., Zastosowanie laserów do fotodynamicznej metody rozpoznawania i leczenia nowotworów, X Szkoła Optoelektroniki Zegrze k/Warszawy, 1995, pp.141–170, (in Polish).
• [2] DYBAŁA F., M.Sc. Thesis, Wrocław University of Technology, Wrocław, Poland, 2000 (in Polish).
• [3] HE GANG, FRANC W. CUOMO, J. Lightwave Technol. 9 (1991), 545.
• [4] Ibidem, p. 1618.