Antibacterial Activities of Some Transition Metal Schiff Base Complexes

• Autorzy: Islam M.N. , Shahriar S.M.S. , Islam M.K. , Jesmin M. , Ali M.M. , Khanam J.A.
• Języki publikacji: EN

Abstrakty

EN

A new series of four transition metal complexes of a Schiff base derived from salicylaldehyde and glycine, viz. [N-salicylidene glycinato diaqua cobalt (II) dimer] (SGCo)2, [N- salicylideneglycinato-di-aqua-nickel(ll)dimer] (SGN)2, [N-salicylideneglycinato-aqua-copper(II)] (SGC) and [N-salicylidene glycinato diaqua zinc(II) dimer] (SGZ)2 have been synthesized and characterized through a rapid, simple, and efficient methodology in excellent yield. These compounds were screened for in vitro antibacterial activities against six pathogenic bacteria, such as Shigella sonnei, Escherichia coli, Bacilus subtilis, Sarcina lutea, Staphylococcus aureus and Pseudomonas arioginosa. The antibacterial activity was determined by the disc diffusion method using DMSO as solvent. The results indicate that (SGC) compound exhibit a significant antibacterial activity, depending on the bacterial strain and (SGCo)2, (SGN)2 and (SGZ)2 compounds show a moderate sensitivity even with higher doses. All these compounds were found to possess cytotoxic effect.

Słowa kluczowe

EN

antibacterial activity; Schiff base transition metal complexes; minimum inhibitory concentration; Brine shrimp lethality

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2013
• Tom: Vol. 5
• Strony: 12--20
• Opis fizyczny: Bibliogr. 16 poz., tab., rys.

Twórcy

autor

Islam M.N.

autor

Shahriar S.M.S.

autor

Islam M.K.

autor

Jesmin M.

autor

Ali M.M.

autor

Khanam J.A.

• 1Department of Applied & Environmental Chemistry, University of Chittagong, Chittagong - 4331, Bangladesh.,

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