Magnetyczna komora badawcza dedykowana do hodowli komórek

• Autorzy: Gawron S. , Glinka M. , Wolnik T.

Warianty tytułu

EN

Magnetic chamber dedicated to research of the cell culture

• Języki publikacji: PL

Abstrakty

EN

At present the most popular, and most commonly applied, permanent magnets are ferrite and neodymium magnets. Their broader and broader industrial use connected with the drop of the costs of their production is connected with the need to broaden the basic tests evaluating their influence upon the functions of living organisms. So far only few studies cited in the world's medical literature have been devoted to the problem of evaluating the activity of permanent magnetic fields onto cell cultures. The permanent magnets used in the studies had no descriptions of their characteristics nor previously prepared spatial models of distribution of the permanent magnetic field intensities. Our goal was an attempt to optimize these studies. We created computer simulations of 3D distribution of the intensities of the permanent magnetic field for several permanent magnets, which, as we assumed, could be used for tests with cell cultures. The next step was the construction of model circuits for several sizes of magnets on the basis of the spatial parameters of a standard plastic container used for growing cell cultures. We compared the assumptions of the intensity simulations with real measurements carried out on models of real circuits. Our research is to be developed in a proposal of a model for testing the impact of permanent magnetic fields on various factors of cell cultures in vitro. Our Assumption are based on the existing 3D simulations carried out for permanent magnets used in the production of electric engines. The calculations of the magnetic induction were carried out with the application of the 3D finite elements method. The results of the measurements were presented in a form of visualization of 3D distribution of the simulations and the real measurements. The measurement differences were statistically compared; no statistically significant differences in the computer simulations (on the basis of the producer's assumptions) and the real measurements were revealed. 3D simulations allow to select appropriate parameters of magnets and to provide design preparation of stations for testing the impact of permanent magnetic fields onto cell cultures.

Słowa kluczowe

PL

magnetyczna komora badawcza; hodowla komórek; magnes trwały

• Wydawca: Sieć Badawcza Łukasiewicz - Górnośląski Instytut Technologiczny
• Czasopismo: Maszyny Elektryczne : zeszyty problemowe
• Rocznik: 2012
• Tom: Nr 4(97)
• Strony: 11--16
• Opis fizyczny: Bibliogr. 10 poz., rys., tab.

Twórcy

autor

Gawron S.

autor

Glinka M.

autor

Wolnik T.

• BOBRME KOMEL,

Bibliografia

• [1]. Glinka T., „Maszyny elektryczne wzbudzane magnesami trwałymi”, Wydawnictwo Politechniki Śląskiej, Gliwice 2002.
• [2]. Bernatt J.: „Obwody elektryczne i magnetyczne maszyn elektrycznych wzbudzanych magnesami trwałymi” Wydawnictwo BOBRME KOMEL Katowice 2010. PL ISBN 978-83-910585-9-6.
• [3]. Bernatt J., Gawron S., „Problemy projektowania i konstrukcji maszyn wzbudzanych magnesami trwałymi”. Jubileusz 90 – lecia Akademii Górniczo-Hutniczej. Materiały Konferencyjne, str. 23-26.
• [4]. Gawron S., Glinka M., Sieroń A., Cieślar G., Pawłowska-Góral K.: „Opracowanie projektu i wykonanie stanowiska badawczego obejmującego: inkubator do hodowli komórek, płyty magnetycznej z magnesami trwałymi i kolbami do hodowli komórek”. Niepublikowane opracowanie BOBRME KOMEL nr CG4-050049, Katowice, grudzień 2010.
• [5]. Gawron S., Glinka M., Sieroń A., Cieślar G., Pawłowska-Góral, K. Wolnik T.: „Rozkłady pola magnetycznego 3D w przestrzeni komory cieplarnianej: obliczenia metodą elementów skończonych, weryfikacja pomiarowa”. Niepublikowane opracowanie BOBRME KOMEL nr CG4-050062, Katowice, lipiec 2011.
• [6]. Bernatt J., Gawron S., Król E.: „Zastosowania trakcyjne nowoczesnych silników z magnesami trwałymi”, Przegląd Elektrotechniczny (Electrical Review) nr 12/2009.
• [7]. Rosen AD „Effects of a 125 mT static magnetic field on the kinetics voltage activated Na+ channels in GH3 cells” Bioelectromagnetics 2003 Oct; 24(7): 517-23.
• [8]. Hughes S., Haj El AJ., Dobson J., Martinac B. “The influence of static magnetic fields on mechanosensitive ion channel activity in artificial liposomes” European Biophysics Journal 2005; 34: 461- 68.
• [9]. Choi JS., Yoo J.: “Optimal design method for magnetization directions of permanent magnet array” Journal of Magnetism and Magnetic Materials 2010; 323: 2145-51.
• [10]. Vokoun D., Tomassetti G., Beleggia M, Stachiv I. “Magnetic forces between arrays of cylindrical permanent magnets” Journal of Magnetism and Magnetic Materials 2011 Jan; 323(1): 55-60.