The effect of hydrotropes on the solubility and mass transfer coefficient of 2-nitrobenzoic acid

• Autorzy: Thenesh-Kumar S. , Gnana-Prakash D. , Nagendra-Gandhi N.
• Języki publikacji: EN

Abstrakty

EN

A comprehensive investigation on the solubility and mass transfer coefficient enhancement of 2-nitrobenzoic acid through hydrotropy, has been undertaken. The solubility and mass transfer coefficient studies were carried out using hydrotropes such as sodium acetate, citric acid and nicotinamide under a wide range of hydrotrope concentrations (0 to 3.0 mol/L) and different system temperatures (303 to 333 K). It was found that the solubility and mass transfer coefficient of 2-nitrobenzoic acid increases with an increase in hydrotrope concentration and also with system temperature. All hydrotropes used in this work showed an enhancement in the solubility and mass transfer coefficient to different degrees. The maximum enhancement factor value has been determined for both the solubility and mass transfer coefficient. The effectiveness of hydrotropes was measured in terms of Setschnew constant Ks and reported for all the hydrotropes used in this study.

Słowa kluczowe

EN

hydrotropy; solubilization; mass transfer coefficient; separation

PL

hydrotrop; solubilizacja; współczynnik wymiany masy; separacja

• Wydawca: West Pomeranian University of Technology. Publishing House
• Czasopismo: Polish Journal of Chemical Technology
• Rocznik: 2009
• Tom: Vol. 11, nr 2
• Strony: 55--59
• Opis fizyczny: Bibliogr. 32 poz., rys., tab.

Twórcy

autor

Thenesh-Kumar S.

autor

Gnana-Prakash D.

autor

Nagendra-Gandhi N.

• St. Peter's Engineering College, Department of Chemical Engineering, Chennai-600 054, India,

Bibliografia

• 1. Neuberg, C. (1916). Hydrotropy. Biochem. Z. 76, 107-108.
• 2. Badwan, A.A., Khordagui L.K.E. & Salesh A. M. (1982). The Solubility of Benzodiazepines in Sodium Salicylate Solutions and a Proposed Mechanism for Hydrotropic Solubilization. Int. J. Pharm. 13, 67-74.
• 3. Balasubramanian, D., Srinivas V., Gaikar V. G. & Sharma M. M. (1989). Aggregation Behaviour of Hydrotropic Compounds in Aqueous Solutions. J. Phys. Chem. 93, 3865-3870.
• 4. Friberg, S. E. & Brancewicz C. (1994). O/W Microemulsions and Hydrotropes: The Coupling Action of a Hydrotrope. Langmuir. 10, 2945-2949.
• 5. Raynaud-Lacroze, P.O. & Tavare N. S. (1993). Separation of 2-naphthol: Hydrotropy and Precipitation. Ind. Eng. Chem. Res. 32, 685-691.
• 6. Laxman, M. & Sharma M. (1990). Reduction of Isophorone with Borohydride: Change in Regio Selectivity with Hydrotropes. Synth. Commun. 20, 111-117.
• 7. Maheswari, R.K. (2006). Novel application of hydrotopic solubilization in the analysis of bulk sample of ketoprofen and salicylic acid. Asian J. Chem. 18, 393-396.
• 8. Gaikar, V.G. & Phatak P.V. (1993). Solubility o- and p-Chlorobenzoic Acid in Hydrotrope Solutions. J. Chem. Eng. Data. 38, 217-220.
• 9. Colonia, E.J., Dixit A.B. & Tavare N.S. (1998). Phase Relations of o- and p- Chlorobenzoic Acids in Hydrotrope Solutions. J. Chem. Eng. Data. 43, 220-225.
• 10. Hodgdon, T.K. & Kaler E.W. (2007). Hydrotropic solutions. Curr Opin Colloid Interface Sci. 12, 121-128.
• 11. Ooya, T., Huh K.M., Saitoh M., Tamiya E. & Park K. (2005). Self-assembly of cholesterol-hydrotropic dendrimer conjugates into micelle-like structure: Preparation and hydrotropic solubilization of paclitaxel. Sci Technol Adv Mater. 6, 452-456.
• 12. Rovetto, L.J., Strobel T.A., Koh C.A. & Sloan Jr.E.D. (2006). Is gas hydrate formation thermodynamically promoted by hydrotrope molecules? Fluid Phase Equilib. 247, 84-89.
• 13. Agarwal, M. & Gaikar V. G. (1992). Extractive Separation Using Hydrotropes. Sep. Technol. 2, 79-84.
• 14. Gaikar, V.G. & Sharma M.M. (1986). Extractive Separation with Hydrotropes. Solvent Extr. Ion Exch. 4, 839-846.
• 15. Mahapatra, A., Gaikar V.G. & Sharma M.M. (1988). New Strategies in Extractive Distillation; Use of Aqueous Solution of Hydrotropes and Organic Bases as Solvent for Organic Acids. Sep. Sci. Technol. 23, 429-436.
• 16. Agarwal, M. & Gaikar V.G. (1992). Extractive distillation with aqueous solutions of hydrotropes, Chem. Eng. Commun. 115, 83-94.
• 17. Friberg, S.E., Yang J. & Huang T. (1996). Reversible Extraction Process of Phenyl Ethyl Alcohol, a Fragrance. Ind. Eng. Chem. Res. 35, 2856-2859.
• 18. Gaikar, V.G. & Phatak P.V. (1999). Selective Solubilisation of Isomers in Hydrotrope Solution o-/p-Chlorobenzoic acids and o-/p-Nitro anilines. Sep. Sci. Technol. 34, 439-459.
• 19. Hefa C. & David S. (2007). Separation of organic compounds from surfactant solution: A Review. Sep. Sci. Technol. 42, 453-475.
• 20. Nagendra-Gandhi, N., Dharmendira-Kumar M. & Sathyamurthy N. (1998). Effect of Hydrotropes on Solubility and Mass-Transfer Coefficient of Butyl Acetate. J. Chem. Eng. Data. 43, 695-699.
• 21. Nagendra-Gandhi, N., Dharmendira-Kumar M. & Sathyamurthy N. (1998). Solubility and Mass Transfer Coefficient Enhancement of Ethyl Benzoate through Hydrotropy. Hungarian J. Ind. Chem. 26, 63-68.
• 22. Nagendra-Gandhi, N. & Dharmendira-Kumar M. (2000). Effect of Hydrotropes on Solubility and Mass Transfer Coefficient of Amyl Acetate. Bioprocess Eng. 23, 31-36.
• 23. Nagendra-Gandhi, N. & Dharmendira-Kumar, M. (2000). Effect of Hydrotropes on Solubility and Mass Transfer Coefficient of Methyl Salicylate. J. Chem. Eng. Data, 45, 419-423.
• 24. Meyyappan N. & Nagendra-Gandhi, N. (2004). Solubility and Mass Transfer Coefficient Enhancement of Benzyl Acetate in Water through Hydrotropy. J. Chem. Eng. Data. 49, 1290-1294.
• 25. Meyyappan, N. & Nagendra Gandhi N. (2005). Solubility and Mass Transfer Coefficient Enhancement of Benzyl Benzoate in Water through Hydrotropy. J. Chem. Eng. Data. 50, 796-800.
• 26. Agrawal, S., Pancholi S.S., Jain N.K. & Agrawal G.P. (2004). Hydrotropic Solubilization of nimesulide for parenteral administration, Int. J. Pharm. 274, 149-155.
• 27. Nicoli, S., Zani F., Bilzi S., Bettini R. & Santi P. (2008). Association of nicotinamide with parabens: Effect on solubility, partition and transdermal permeation. Eur J Pharm Biopharm. 69, 613-621.
• 28. Dandekar, D.V., Jayaprakasha G.K. & Patil B.S. (2008). Hydrotropic extraction of bioactive limonin from sour orange (Citrus aurantium L.) seeds, Food Chem. 109, 515-520.
• 29. John, A.D. (1987). Lange's Handbook of Chemistry (13th ed.). New York: McGraw-Hill
• 30. Perry, R.H. (1997). Perry's Chemical Engineer's Handbook (7th ed.). New York: McGraw-Hill.
• 31. Miguel, G.N., Carla C.S., Katia R.P. & Beatriz E.G. (2007). The photophysical determination of the minimum hydrotrope concentration of aromatic hydrotropes. J. Colloid and Interface Sci. 315, 810-813.
• 32. Wagle, V.B, Kothari P.S & Gaikar V.G. (2007). Effect of temperature on aggregation behaviour of aqueous solution of sodium cumene sulfonate. J. Mol Liq. 133, 68-76.