Bioinformatyczna analiza przewidywanego klastra genów biosyntezy (+)-geodyny u Aspergillus terreus

• Autorzy: Boruta T. , Bizukojć M. , Ledakowicz S.

Warianty tytułu

EN

Bioinformatic analysis of the predicted (+)-geodin biosynthesis gene cluster of Aspergillus terreus

• Języki publikacji: PL

Abstrakty

PL

Klaster genów odpowiedzialny za biosyntezę (+)-geodyny u Aspergillus terreus został zidentyfikowany i opisany przy użyciu narzędzi bioinformatyki. Ustalono hipotetyczne funkcje produktów kodowanych przez geny klastra opisano je w kontekście proponowanego szlaku biosyntezy (+)-geodyny. Analiza pokazała, że metody in silico używane w analizie szlaków metabolicznych mogą dostarczyć cennych wskazówek dla badaczy, ale powinny być wspierane danymi eksperymentalnymi.

EN

The cluster of genes responsible for (+)-geodin biosynthesis in Aspergillus terreus was identified and described using the tools of bioinformatics. Hypothetical functions of proteins encoded by the cluster genes were established and discussed in the context of proposed (+)-gcodin biosynthesis pathway. The analysis showed that in silico methods employed in metabolic pathway analysis may provide useful guidelines for researchers, but should be always supported with experimental data.

Słowa kluczowe

PL

Aspergillus; (+)-geodyna; poliketydy; BLAST

EN

Aspergillus; (+)-geodin; polyketides; BLAST

• Wydawca: Stowarzyszenie Inżynierów i Techników Mechaników Polskich
• Czasopismo: Inżynieria i Aparatura Chemiczna
• Rocznik: 2012
• Tom: Nr 4
• Strony: 92--94
• Opis fizyczny: Bibliogr. 15 poz.

Twórcy

autor

Boruta T.

autor

Bizukojć M.

autor

Ledakowicz S.

• Katedra Inżynierii Bioprocesowej, Wydział Inżynierii Procesowej i Ochrony Środowiska, Politechnika Łódzka, Łódź

Bibliografia

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