Modelowanie metabolizmu w erze inżynierii biologicznej

• Autorzy: Boruta T. , Bizukojć M. , Ledakowicz S.

Warianty tytułu

EN

Metabolic modelling in the era of biological engineering

• Języki publikacji: PL

Abstrakty

PL

Współczesna inżynieria metaboliczna oparta jest na narzędziach biologii systemów i biologii syntetycznej. Modelowanie matematyczne odgrywa istotną rolę w badaniach związanych z modyfikacją sieci metabolicznej, ponieważ pozwala w sposób ilościowy analizować system biologiczny. Analiza bilansu strumieni pozwala na wyznaczenie wartości strumieni w sieci poprzez maksymalizację biologicznej funkcji celu. Algorytmy inżynierii metabolicznej in silico oparte są na procedurach optymalizacji.

EN

Modern metabolic engineering is based on the tools of systems biology and synthetic biology. Mathematical modelling plays an important role in the research related to metabolic network modification, because it enables one to analyze the biological system in a quantitative manner. The flux balance analysis enables one to determine flux values in the network by maximizing the biological objective function. Algorithms of in silico metabolic engineering are based on optimization procedures.

Słowa kluczowe

PL

metabolizm; model; optymalizacja; bioinżynieria; algorytm

EN

metabolism; model; optimization; bioengineering; algorithm

• Wydawca: Stowarzyszenie Inżynierów i Techników Mechaników Polskich
• Czasopismo: Inżynieria i Aparatura Chemiczna
• Rocznik: 2012
• Tom: Nr 4
• Strony: 89--91
• Opis fizyczny: Bibliogr. 26 poz.

Twórcy

autor

Boruta T.

autor

Bizukojć M.

autor

Ledakowicz S.

• Katedra Inżynierii Bioprocesowej, Wydział Inżynierii Procesowej i Ochrony Środowiska, Politechnika Łódzka, Łódź,

Bibliografia

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