Physical image vs. structure relation, 4[1]. Configuration and conformation determination of some bicyclic lactams by 1H NMR and theoretical methods

• Autorzy: Nazarski R. B. , Leśniak S.
• Języki publikacji: EN

Abstrakty

EN

Resolution-enhanced H NMR spectra of six single diastereomers of fused-ring sulfur-containing lactams have been recorded and interpreted. In joint analysis of derived couplings Ť/HH> performed with use of the Karplus-Conroy type relationship and results of static MM calculations, it was possible to determine the configuration of title compounds and the conformation elucidation of their six-membered rings. Simultaneously, the stereochemistry of the observed ring-closure reaction was determined. The application of TNDO/2 method for the prediction of n JHH values is also briefly discussed.

Słowa kluczowe

EN

lactam; interproton coupling; Karplus-Conroy relation; diastereomers; H NMR

PL

laktam; sprzężenie protonowe; Karplus-Conroy zależność; diasteroizomer; rezonans jądrowy magnetyczny

• Wydawca: Centrum Upowszechniania Nauki PAN
• Czasopismo: Bulletin of the Polish Academy of Sciences. Chemistry
• Rocznik: 2000
• Tom: Vol. 48, No. 1
• Strony: 17--25
• Opis fizyczny: Bibliogr. 22 poz.

Twórcy

autor

Nazarski R. B.

autor

Leśniak S.

• Department of Organic Chemistry, University of Łódź, Narutowicza 68, 90-136 Łódź 1, P.O. Box 376, Poland (RBN) (Katedra Chemii Organicznej, Uniwersytet Łódzki),